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Last updated on April 23, 2014 at 1:22 EDT

Latest BMI1 Stories

2013-06-18 13:52:00

-A protein called Nanog helps the renewal of healthy embryonic stem cells. -This study shows that Nanog also promotes cancer stem cell proliferation in head and neck cancer and shows how it promotes their growth. -The findings could lead to new, novel treatments for head and neck cancer. A new study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) has...

2012-07-11 02:25:53

SOUTH PLAINFIELD, N.J., July 11, 2012 /PRNewswire/ -- PTC Therapeutics, Inc. (PTC) today announced that it has selected an experimental drug candidate to advance in its BMI1 program for aggressive and drug-resistant tumors. The milestone triggers drawdown of the next $2.3 million installment of its Seeding Drug Discovery Award from the Wellcome Trust. (Logo: http://photos.prnewswire.com/prnh/20010919/PTCLOGO) The candidate, PTC596, is a first-in-class, oral, potent and selective inhibitor...

2011-06-06 07:58:03

(Ivanhoe Newswire) -- Researchers have discovered a way of eliminating leukemic stem cells, which could lead to new treatments that may help leukemia patients achieve complete remission. The study showed leukemic stem cells can be abolished by suppressing two proteins found in the bodies of mice. Researchers say leukemic stem cells are responsible for sustaining the disease and are most likely responsible for relapse. Eliminating these cells is believed to be the key for complete remission....

2011-06-02 23:46:04

Researchers at King's College London have identified a way of eliminating leukemic stem cells, which could lead to new treatments that may enable complete remission for leukemia patients Researchers at King's College London have identified a way of eliminating leukaemic stem cells, which could lead to new treatments that may enable complete remission for leukaemia patients. An early study in mice has shown that leukaemic stem cells can be abolished by suppressing two proteins found in the...

2011-03-02 07:00:00

SOUTH PLAINFIELD, N.J., March 2, 2011 /PRNewswire/ -- PTC Therapeutics, Inc. (PTC) today announced that it has identified a chemical series of molecules that penetrates the blood-brain barrier in animal models and reduces levels of BMI1, a protein linked to drug-resistant cancers. The research marks a milestone in PTC's collaboration with the Wellcome Trust and triggers drawdown of a $2.2 million tranche of their $5.4 million Seeding Drug Discovery award. (Logo:...

2009-01-19 13:09:46

Canadian researchers have identified a gene that controls the normal and pathological aging of neurons in the central nervous system: Bmi1. A research team from the University of Montreal, Maisonneuve-Rosemont Hospital and Lawrence Berkeley National Laboratory said the primary risk factor for diseases such as macular degeneration, Parkinson's and Alzheimer's is age. Although many researchers have sought to better understand the genetics and pathophysiology of these diseases, few studies have...

2009-01-16 11:20:39

Will scientists one day be able to slow the aging of the brain and prevent diseases such as Alzheimer's and Parkinson's? Absolutely "“ once the genetic coding associated with neuronal degeneration has been unraveled.According to a new study published in The Journal of Neuroscience, a research team from the Universit© de Montr©al, Maisonneuve-Rosemont Hospital and Lawrence Berkeley National Laboratory has taken a giant step in this direction by identifying a gene that controls...