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Last updated on April 16, 2014 at 5:49 EDT

Latest Bone density Stories

2009-08-14 11:07:47

Amgen's bone drug, denosumab, has been partially endorsed by an advisory committee to the U.S. Food and Drug Administration, officials said. In a unanimous vote Thursday, the committee said denosumab should be approved to treat post menopausal women with osteoporosis, The New York Times reported Friday. However, the committee voted 12 to 3 against denosumab being used to prevent osteoporosis in women with moderately low bone density, and it opposed three of four possible uses for prostate and...

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2009-08-12 14:52:34

Studies suggest that a first-of-its-kind osteoporosis drug lowers the risk of bone fractures better than some existing treatments and could soon add a more expensive but easier option to the booming market, The Associated Press reported. Amgen Inc's genetically engineered denosumab only requires two shots a year and could be approved for sale this fall. Many osteoporosis patients stop taking other drugs due to side effects or frequent dosing. But doctors say denosumab's high cost may be a...

2009-08-11 09:05:00

THOUSAND OAKS, Calif., Aug. 11 /PRNewswire-FirstCall/ -- Amgen Inc. (Nasdaq: AMGN) today announced the publication of results from two pivotal Phase 3 studies investigating the safety and effectiveness of denosumab at reducing fracture risk in more than 7,800 women with postmenopausal osteoporosis and in more than 1,400 men with non-metastatic prostate cancer undergoing androgen deprivation therapy (ADT) leading to bone loss. In both studies, published today in The New England Journal of...

2009-08-07 09:00:20

According to the National Osteoporosis Foundation, in the United States, about 300,000 people fracture their hip every year, and about 20 percent of these people die of their fracture within a year. Stroke patients have about twice the increased risk of breaking a hip or femur, than those who have not suffered stoke, according to reports from a recent study.In the study, a team of Dutch researchers looked at 6,763 patients who had a hip or femur fracture and compared them to 26,341 people who...

2009-08-06 15:28:24

Stroke survivors have about twice the risk of breaking a hip or femur compared to those without stroke "” and the risk is even greater for younger patients, women and those with recent strokes, Dutch researchers report in Stroke: Journal of the American Heart Association."Our findings imply that it is important to conduct fracture risk assessment immediately after a patient is hospitalized for stroke," said Frank de Vries, Ph.D., senior author of the study and assistant professor of...

2009-08-05 07:30:00

CAMBRIDGE, Mass., Aug. 5 /PRNewswire/ -- Radius Health ("Radius") today announced topline Phase 2 data demonstrating that in women with osteoporosis, BA058 -- the company's novel PTHrP (parathyroid hormone-related protein) analog -- significantly increased bone mineral density (BMD) at the lumbar spine and femoral neck (a common fracture site located in the hip joint) after six months of therapy. The gains in lumbar spine and femoral neck BMD were further increased in a subset of patients...

2009-07-28 04:00:00

CLEVELAND, July 28 /PRNewswire/ -- More than 340,000(2) women suffer from postmenopausal osteoporosis (PMO) in Ohio and more than 900,000(3) are at risk for the disease. According to a census report on the prevalence of osteoporosis, the number of women suffering from the disease is predicted to increase in Ohio by more than 22 percent by 2020. Despite this predicted increase, a national Harris Interactive survey commissioned by the Know My Bones Council showed (n=889 with PMO; n=912...

2009-06-25 07:24:45

Regular bone mineral density monitoring in postmenopausal women may be unnecessary and potentially misleading. Researchers looked at how the effects of the drug alendronate (a widely used osteoporosis drug) differ between individuals. They found after three years therapy, almost all (97.5%) women treated with alendronate showed at least a modest increase in hip bone mineral density. In addition, this treatment effect did not vary substantially between individuals. Researchers say this makes...

2009-06-24 07:58:29

Monitoring bone mineral density in postmenopausal women taking osteoporosis drugs (bisphosphonates) is unnecessary and potentially misleading, concludes a study published on bmj.com today.Osteoporosis is a major public health problem, particularly in older women because bone density falls after the menopause as oestrogen levels dwindle. Low bone mineral density is an important risk factor for fractures.Some guidelines recommend regular monitoring of bone mineral density in postmenopausal...

2009-06-02 08:05:00

Up to 50 percent of RA patients show evidence of focal erosions, and RA doubles the risk of osteoporosis and fracturesRheumatoid arthritis (RA), the most common form of inflammatory arthritis, affects almost three percent of people over age 65. RA patients experience pain, functional limitations and two forms of disabling bone disease: focal erosions and osteoporosis. After five years of disease, up to 50 percent of RA patients show evidence of focal erosions and RA doubles the risk of...