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Latest Botulism Stories

2010-02-25 09:13:42

Strategy proven for botulism; may lead to improved therapies for many toxins and some chronic diseases A study involving the world's deadliest substance has yielded a new strategy to clear toxins from the body"”which may lead to more efficient strategies against toxins that may be used in a bioterrorist event, as well as snake bites, scorpion stings, and even some important chronic diseases. A Tufts-led team developed the new strategy to deliver small binding agents that seek out...

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2010-01-21 10:20:00

The finding may lead to improved techniques for testing water and food supplies should botulinin neurotoxins be used as a bioterrorism weapon Scientists at the Southwest Foundation for Biomedical Research (SFBR) have for the first time developed a highly sensitive means of detecting the seven types of botulinum neurotoxins (BoNTs) simultaneously. The BoNT-detecting substances are antibodies -- proteins made by the body to fight diseases -- found in llamas. BoNT are about 100 billion times...

2009-07-07 04:20:00

SCOTTSDALE, Ariz., July 7 /PRNewswire/ -- Americans aren't willing to give up aesthetic injections and interest is growing, whether as a means to stay competitive in today's job market or simply to maintain a youthful image, the demand and want is strong. At the time of a recent Kelton Research* survey more than 40 percent of respondents were interested in receiving aesthetic botulinum toxin injections within the next six months.(1) Despite clear interest, many expressed reluctance to...

2009-06-10 11:04:52

The U.S. Food and Drug Administration has ordered safety label changes, including a boxed warning, for all botulinum toxin products. The federal agency said it took the action because of reports that the effects of the botulinum toxin may spread from the area of injection to other areas of the body, causing symptoms similar to those of botulism. Those symptoms include muscle weakness; difficulty talking, breathing and swallowing; loss of bladder control; vision problems and drooping eyelids....

2009-05-14 19:39:38

Two Canadian agencies have issued a food safety warning for home canning and bottling of seafood. Officials of Ottawa Health Canada and the Canadian Food Inspection Agency remind home canners and consumers that home canning and bottling of seafood is popular in Canada, but food safety awareness should be the priority when home canning or when buying home canned products from vendors. Improper preparation, canning or storage, especially of low-acid foods such as clams, lobster and whelks,...

2009-05-04 10:15:25

The U.S. Food and Drug Administration says it has ordered safety label changes, including a boxed warning, for all botulinum toxin products. The federal agency said it took the action because of reports that the effects of the botulinum toxin may spread from the area of injection to other areas of the body, causing symptoms similar to those of botulism. Symptoms include unexpected loss of strength or muscle weakness, hoarseness or trouble talking, trouble saying words clearly, loss of bladder...

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2009-04-30 15:40:00

U.S. regulators warned consumers and doctors on Thursday about potentially deadly complications that can arise from off-label use of Allergan Inc.'s Botox and similar drugs. The U.S. Food and Drug Administration (FDA) said the wrinkle-smoother Botox and two other injections carry risks of rare botulism symptoms, especially when given to children to treat muscle spasms. Botulinum toxin can paralyze or relax muscles.  Although the drug is perhaps best known for its use as a wrinkle...

2009-01-08 16:40:00

A preclinical study found a new nasal spray vaccine to provide complete protection against a major botulism toxin, according to a study published today in the Nature journal Gene Therapy.Botulism is caused by a bacterium, Clostridium botulinum, which produces toxins that cause paralysis and often death, as the muscles that control breathing fail. Out of an average of 145 U.S. cases each year, 65 percent are infant botulism (infants' intestines, unlike adults, are vulnerable to...

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2008-12-23 09:23:02

Findings may explain faster action with implications for toxicity and therapeutic use Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a third subtype of botulinum neurotoxin "” a deadly toxin produced by certain bacteria that causes the disease botulism, and is also used in cosmetic and therapeutic applications such as reducing wrinkles and calming a hyperactive bladder. The detailed structure, published...

2008-12-15 11:11:14

The U.S. Food and Drug Administration is warning about the sale or consumption of certain imported ungutted, salt-cured alewives fish from Canada. The FDA said the fish -- also called gaspereaux fish -- were imported from Michel & Charles LeBlanc Fisheries Ltd. of New Brunswick, Canada, and might contain Clostridium botulinum, a bacterium that can cause botulism, a serious and sometimes life-threatening condition. The toxin cannot be removed by cooking or freezing. The federal agency said...


Latest Botulism Reference Libraries

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2011-04-15 13:32:47

Clostridium botulinum is a gram-positive, rod-shaped bacterium that produces neurotoxins, known as botulinum neurotoxins types A-G, that cause the flaccid muscular paralysis seen in botulism. It is the main paralytic agent in botox and is commonly found in soil. It is also an obligate anaerobe, meaning oxygen is poisonous to the cells. Superoxide dismutase helps C. botulinum tolerate traces of oxygen. It was first recognized and isolated in 1895 by Emile van Ermengem. Subsequent outbreaks...

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Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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