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Latest Brain-derived neurotrophic factor Stories

2009-12-09 19:44:52

Cells release nourishing growth factor in key area Nerve cells transplanted into brain-damaged rats helped them to fully recover their ability to learn and remember, probably by promoting nurturing, protective growth factors, according to a new study. Building on previous investigation of transplants in the nervous system, this critical study confirms that cell transplants can help the brain to heal itself. Ultimately, it may lead to new therapies to help dementia patients. More generally,...

2009-10-28 14:25:00

People with gene variant perform more than 20 percent worse on driving test Bad drivers may in part have their genes to blame, suggests a new study by UC Irvine neuroscientists. People with a particular gene variant performed more than 20 percent worse on a driving test than people without it - and a follow-up test a few days later yielded similar results. About 30 percent of Americans have the variant. "These people make more errors from the get-go, and they forget more of what they learned...

2009-10-20 19:19:28

Growth factors. They are the proteins that trigger a countless number of actions in cells. Drugs that increase or decrease certain growth factors have lead to treatments for cancer and cardiovascular diseases. Georgetown University Medical Center researchers say a new understanding of a growth factor implicated in some mental retardation disorders could lead to a novel treatment. Abnormalities in the number and shape of dendritic spines, the protrusions that allow communication between brain...

2009-10-20 07:00:00

ST. LOUIS, Oct. 20 /PRNewswire-FirstCall/ -- Sigma-Aldrich® (Nasdaq: SIAL) today announced the launch of the SAGE(TM) Priority Partners Program, through which the Company plans to build a network of researchers to evaluate the 'knockout' rat models it is developing to support pre-clinical research work across a number of medical fields, including Neurobiology, Toxicology, Cardiology, Immunology and others. The partner program, managed by Sigma Advanced Genetic...

2009-10-06 14:27:11

The action of a small protein that is a major villain in Alzheimer's disease can be counterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study. The findings, available online in the journal Proceedings of the National Academy of Sciences, suggest a promising new tactic against the devastating illness, the researchers said. The harmful protein, called beta-amyloid, is found in the brain and, when functioning properly, suppresses...

2009-09-30 07:27:11

Chaos brews in the brains of newborns: the nerve cells are still bound only loosely to each other. Under the leadership of Academy Research Fellow Sari Lauri, a team of researchers at the University of Helsinki has been studying for years how a neural network capable of processing information effectively is created out of chaos. The team has now found a new kind of mechanism that adjusts the functional development of nerve cell contacts. The results were published in early September as the...

2009-07-21 14:02:57

UC Irvine scientists have shown for the first time that neural stem cells can rescue memory in mice with advanced Alzheimer's disease, raising hopes of a potential treatment for the leading cause of elderly dementia that afflicts 5.3 million people in the U.S.Mice genetically engineered to have Alzheimer's performed markedly better on memory tests a month after mouse neural stem cells were injected into their brains. The stem cells secreted a protein that created more neural connections,...

2009-06-23 11:10:29

Eating disorders are frequently seen as psychological or societal diseases, but do they have an underlying biological cause? A new study shows that the levels of a brain protein differ between healthy and anorexic women.Anorexia is a serious and occasionally fatal eating disorder most commonly affecting women. Scientists do not yet understand the physical causes of anorexia, though some studies suggest a link to low levels of a brain protein called BDNF. Now, a study recommended by Cynthia...

2009-05-29 08:59:43

When someone becomes dependent on drugs or alcohol, the brain's pleasure center gets hijacked, disrupting the normal functioning of its reward circuitry. Researchers investigating this addiction "switch" have now implicated a naturally occurring protein, a dose of which allowed them to get rats hooked with no drugs at all. The research will be published Friday in the journal Science. "If we can understand how the brain's circuitry changes in association with drug abuse, it could potentially...

2009-05-18 15:42:01

The instruction manual for maintaining an efficient brain may soon include a section on synaptotagmin-IV (Syt-IV), a protein known to influence learning and memory, thanks to a study by University of Wisconsin-Madison researchers.The study showed that Syt-IV keeps the strength of synapses "” connections between nerve cells where communication occurs "” within a useful range of neither too strong nor too weak.Synapses' ability to adjust over time by becoming bigger and stronger or...


Word of the Day
ambsace
  • Bad luck; misfortune.
  • The smallest amount possible or the most worthless thing.
The word 'ambsace' comes from a Latin word meaning 'both'.