Latest BRCA1 Stories
NEW YORK (Reuters Health) - Women with BRCA1 gene mutations, which confer a high risk of developing breast cancer, might decrease their risk by drinking a lot of coffee, according to a multicenter team of investigators. Dr. Steven A. Narod, of the University of Toronto, Ontario, and colleagues examined the association between coffee consumption and the risk of breast cancer among 1690 high-risk women with BRCA1 or BRCA2 mutations. The study included women from 40 clinical centers in...
NEW YORK -- Women with BRCA1 gene mutations, which confer a high risk of developing breast cancer, might decrease their risk by drinking a lot of coffee, according to a multicenter team of investigators.Dr. Steven A. Narod, of the University of Toronto, Ontario, and colleagues examined the association between coffee consumption and the risk of breast cancer among 1690 high-risk women with BRCA1 or BRCA2 mutations.The study included women from 40 clinical centers in four countries. A...
By Megan Rauscher NEW YORK (Reuters Health) - Genetic mutations in the breast cancer susceptibility genes -- BRCA1 and BRCA2 -- occur with "appreciable frequency" in African-American women with a family history of the disease, with more than one quarter testing positive for a mutation in one of these genes that indicates high risk, a study shows. This finding supports genetic testing for BRCA1 and BRCA1 mutations in high-risk African American families, study investigators report in...
NEW YORK, September 21, 2005 "“ Women with a strong family history of breast cancer but who don't have breast cancer genetic mutations can now be reassured that they are not at increased risk for ovarian cancer, according to a new study by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC). The work, published in the September 21, 2005, issue of the Journal of the National Cancer Institute, is one of the first prospective studies to allow doctors to tailor ovarian cancer...
Surprising findings from just five patients has led to the first proof of how the rare disorder Fanconi anemia causes chromosomal instability. A team of international researchers, led by scientists at Rockefeller University, reports the findings in the September issue of Nature Genetics. The scientists found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the disease whose protein has a known function. That...
LONDON -- Scientists said on Thursday they had pinpointed four new genes believed to be involved in the development of breast cancer.By examining tissue from 53 breast cancer tumors and cells grown in the laboratory, researchers at the University of Cambridge in England narrowed down the search for the genes that that could provide a basis for new treatments for the disease."By using the latest in DNA technology we've been able to pinpoint four new genes likely to be involved in the...
PHILADELPHIA -- For about a decade, scientists have recognized that many cases of hereditary breast cancer result from a mutation of a specific gene called BRCA1, which, in its normal state, helps keep tumor formation in check. About five to 10 percent of breast cancer cases are linked to genetic miscues, about half of which are linked to BRCA1. But now scientists have discovered that a protein called cyclin D1, grossly overproduced in about half of all cases of breast cancer, can also...
