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Latest BRCA1 Stories

2010-10-05 07:30:00

CAMBRIDGE, Mass., Oct. 5 /PRNewswire/ -- Knome, Inc. today announced the winners of its inaugural KnomeDISCOVERY Awards, a program designed to spur new genetic insights into health. Researchers Judith Conroy (University College Dublin, Ireland), Eitan Friedman (Sheba Medical Center, Israel), and Abhimanyu Garg (University of Texas-Southwestern Medical Center, USA) have been awarded KnomeDISCOVERY(TM) exome sequencing and comparative analysis packages. Each winner will use Knome's...

2010-09-20 18:50:44

Individuals with disrupting mutations in the BRCA1 gene are known to be at substantially increased risk of breast cancer throughout their lives. Now, discoveries from an international research team led by Mayo Clinic researchers show that some of those persons may possess additional genetic variants that modify their risk. These new findings enhancing individualized medicine appear in the current Nature Genetics. "These findings should be useful in helping determine individual risk for breast...

2010-09-20 18:46:39

An international consortium of scientists has discovered new genetic variants in five regions of the genome that affect the risk of ovarian cancer in the general population, according to two separate studies published today (Sunday), online in Nature Genetics. The consortium, including scientists from the U.S., Europe, Canada and Australia, based the new work on their earlier research comparing 10,283 women with ovarian cancer to 13,185 women without the disease. That effort had found a...

2010-09-02 12:41:44

New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study, published by Cell Press in the September 3rd issue of the journal Cell Stem Cell, suggests that despite their "stem cell-like" characteristics, most aggressive breast tumors are not derived from normal mammary gland stem cells. The glandular tissue of the breast contains two main cell types, outer "basal" cells and inner "luminal" cells....

2010-09-01 14:21:19

Women at increased risk of breast and ovarian cancer because of inherited mutations of the BRCA1 or BRCA2 genes who had prophylactic mastectomy or salpingo-oophorectomy (removal of the fallopian tubes and ovaries) had an associated decreased risk of breast cancer and ovarian cancer, according to a study in the September 1 issue of JAMA. "Women who have inherited mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have substantially elevated risks of breast cancer and ovarian cancer, with a...

2010-09-01 14:11:42

Genetic testing is critical for women with family history of ovarian and breast cancers A new study underscores the importance for women with a family history of breast or ovarian cancer to get genetic counseling and testing for the BRCA1 and BRCA2 genes that make them more likely to develop lethal breast or ovarian cancer, says a Northwestern Medicine oncologist. The study, which will be published in the Sept. 1 issue of the Journal of the American Medical Association (JAMA), shows women...

2010-09-01 08:43:08

(Ivanhoe Newswire) -- A recent study underscores the importance of genetic counseling and testing for women with family history of breast or ovarian cancer.  Research shows women with the BRCA1 and BRCA2 genes live longer and virtually eliminate their risk of cancer by having prophylactic surgeries to remove their ovaries and fallopian tubes or their breast in a mastectomy. "This is the first study to prove women survive longer with these preventative surgeries and shows the importance...

2010-05-13 10:00:00

LANSDALE, Pa., May 13 /PRNewswire/ -- A guide to BRCA1 and BRCA2 genetic testing has been released by Hayes, Inc. This comprehensive resource is designed to equip physicians and other healthcare professionals who are not trained in genetics with independent, evidence-based information to help them understand the complexities of BRCA1/2 gene testing. According to the American Cancer Society, breast cancer is the most common cancer among American women, except for skin cancers. Women who...

2009-12-23 16:54:52

Genome rearrangements in 24 breast cancers The first detailed search of breast cancer genomes to uncover genomic rearrangements is published today. The team characterized the ways in which the human genome is broken and put back together in 24 cases of breast cancer. Rearrangements involve reshuffling and reorganization of the genome and include deletions, duplications and novel juxtaposition of DNA sequences. The study shows that breast cancer samples can differ greatly in the extent to...

2009-12-19 00:15:25

New findings may help explain why women who carry a mutated BRCA1 gene have greater rates of infertility as well as a greater risk for breast and ovarian cancer A New York Medical College physician who specializes in restoring or preserving fertility in female cancer patients has discovered a possible link between the presence of breast cancer genes and infertility. In a paper published last week in the Journal of Clinical Oncology, Kutluk Oktay, M.D., professor of obstetrics and gynecology...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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