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Last updated on April 17, 2014 at 21:23 EDT

Latest BRCA2 Stories

2011-04-04 19:37:00

Women with ovarian cancer who have the BRCA2 gene mutation are more likely to survive the malignancy than women with the BRCA1 mutation, or women without either mutation. In results presented at the AACR 102nd Annual Meeting 2011, held April 2-6, Kelly Bolton, a fellow at the National Cancer Institute, said the findings describe the effect of these mutations in ovarian cancer survival. "There was some previous evidence that women with ovarian cancer who have mutations in the BRCA genes show...

2011-02-18 16:32:47

Between 5 % and 10 % of breast cancer cases are hereditary, arising because the patient inherits from the father or mother a mutation in a gene that is susceptible to causing the illness. BRCA1 and BRCA2 have already been identified as two of the genes to be monitored. It is estimated that 30 % of hereditary breast cancer cases are due to mutations in one of these two genes (which suggests, at the same time, that there are other genes involved, but exactly how is still unknown). In any case,...

2010-10-29 18:46:19

An international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer. The study was published today online in the open-access journal PLoS Genetics. The findings of the study suggest that genetic variants on chromosomes 10 and 20 may modify risk for breast cancer among women with a BRCA2 mutation. Researchers analyzed DNA samples from 6,272 women...

2010-10-28 08:13:51

(Ivanhoe Newswire) -- When you go to a new doctor and fill out your family history, beware! Seems paternal history is just as important as maternal history. About 5% of breast and ovarian cancer cases are the result of an inherited genetic predisposition mostly caused by the BRCA1 or BRCA2 genes. These gene mutations increase the risk of cancers in both men and women. But despite both men and women being equally likely to pass this genetic susceptibility to their children, a father's family...

2010-09-01 14:21:19

Women at increased risk of breast and ovarian cancer because of inherited mutations of the BRCA1 or BRCA2 genes who had prophylactic mastectomy or salpingo-oophorectomy (removal of the fallopian tubes and ovaries) had an associated decreased risk of breast cancer and ovarian cancer, according to a study in the September 1 issue of JAMA. "Women who have inherited mutations in the BRCA1 or BRCA2 (BRCA1/2) genes have substantially elevated risks of breast cancer and ovarian cancer, with a...

2010-07-06 12:11:05

New strategy holds promise for fewer patient side effects A novel therapy designed to attack tumors in patients with a genetic mutation in either BRCA1 or BRCA2, slowed tumor growth in 85 percent of advanced breast cancer patients treated in a small study, researchers report in the July 6 issue of the Lancet. "That is really an enormous response rate in a population of patients who have received a median of three prior therapies," says study co-author Susan M. Domchek, MD, associate professor...

2010-05-13 10:00:00

LANSDALE, Pa., May 13 /PRNewswire/ -- A guide to BRCA1 and BRCA2 genetic testing has been released by Hayes, Inc. This comprehensive resource is designed to equip physicians and other healthcare professionals who are not trained in genetics with independent, evidence-based information to help them understand the complexities of BRCA1/2 gene testing. According to the American Cancer Society, breast cancer is the most common cancer among American women, except for skin cancers. Women who...

2009-12-11 09:46:00

Westchester Medical Center Physician and Fertility Preservation Expert leads study examining the association of breast cancer genes, breast cancer and infertility VALHALLA, N.Y., Dec. 11 /PRNewswire-USNewswire/ -- In a study published online this week in the leading cancer journal, Journal of Clinical Oncology, Westchester Medical Center Physician Dr. Kutluk Oktay, MD, Director, Division of Reproductive Medicine & Infertility concluded that mutations in the BRCA1 gene (gene associated...

2009-09-22 07:41:15

Women with mutations in either their BRCA1 or BRCA2 genes have a dramatically increased risk of developing breast or ovarian cancer. Identifying such women provides them with an opportunity to take preventive measures such as surgery to remove their breasts. One caveat to identifying such women by simply sequencing their BRCA1 and BRCA2 genes and detecting mutations is that not all mutations are harmful. However, Shyam Sharan and colleagues, at the National Cancer Institute at Frederick, have...

2009-09-14 08:00:00

SALT LAKE CITY, Sept. 14 /PRNewswire-FirstCall/ -- Myriad Genetics, Inc. (Nasdaq: MYGN) announced today that it has launched a hereditary breast and ovarian cancer Public Awareness Campaign in five Midwest states, including Illinois, Indiana, Kentucky, Missouri and Ohio. The initiative is a comprehensive effort designed to reach women with a family history of breast and/or ovarian cancers and the healthcare providers that treat them. According to the American Cancer Society, more than...