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Latest Breast cancer metastasis Stories

Potential Roadblock For Cancer Found
2012-08-01 13:45:36

By identifying a key protein that tells certain breast cancer cells when and how to move, researchers at Michigan State University hope to better understand the process by which breast cancer spreads, or metastasizes. When breast cancer metastasizes, cancer cells break away from a primary tumor and move to other organs in the body, including the lungs, liver and brain. In work published recently in the journal Cancer Research, MSU researchers Kathy Gallo and Jian Chen show a protein called...

2012-07-26 01:10:11

There are many factors that affect tumor invasion, the process where a tumor grows beyond the tissue where it first developed. While factors like genetics, tissue type and environmental exposure affect tumor metastasis and invasion, physical forces like fluid flow remain a poorly understood component of tumor invasion. A new video article in JoVE, the Journal of Visualized Experiments, describes a novel procedure that allows researchers to study and test the microenvironment of a growing...

2012-07-18 10:29:08

Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered. The studies, reported July 17 in PLoS Biology, demonstrate in mice that activation of the sympathetic nervous system — the "fight-or-flight" response to stress — primes the bone environment for breast cancer cell metastasis. The researchers were able to prevent breast cancer cell lesions in bone using propranolol, a cardiovascular medicine that inhibits...

2012-07-18 06:37:41

(Ivanhoe Newswire) — Investigators from the Vanderbilt Center for Bone Biology have discovered that stress can promote the colonization of breast cancer cells in bone. Mice studies revealed that the activation of the sympathetic nervous system (the "fight or flight" response) primes the bone environment for breast cancer cell metastasis. Researchers were able to prevent breast cancer cell lesions in bone using propranolol, a cardiovascular medicine that inhibits sympathetic nervous...

How Metastasizing Cancer Cells Can Enter Organs
2012-07-11 18:38:46

It is not primary tumors that are responsible for the majority of cancer deaths, but rather their metastases. Physiologists and neuropathologists from the University of Zurich have now identified the origin of metastasis formation, thereby becoming the first to reveal the pathway of metastasizing intestinal cancer cells out of the blood stream. The results allow new approaches in the development of cancer therapies. Every year, over seven million people die of cancer worldwide. Thanks to...

2012-06-15 12:00:47

Preclinical study links aging and cancer, with lethal host metabolism in the tumor microenvironment It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive. Now, researchers at the Kimmel Cancer Center at Jefferson (KCC) have shown that senescence (aging cells which lose their ability to divide) and autophagy (self-eating or self-cannibalism) in the surrounding normal cells of a tumor are essentially two sides of the same coin,...

2012-06-14 12:22:54

An important gene for bone metastasis Breast cancer cells frequently move from their primary site and invade bone, decreasing a patient's chance of survival. This process of metastasis is complex, and factors both within the breast cancer cells and within the new bone environment play a role. In next week's Journal of Biological Chemistry "Paper of the Week," Roger Gomis and colleagues at the Institute for Research in Biomedicine in Spain investigated how breast cancer cells migrate to...

2012-05-29 12:41:39

Cellular particles fuse with organs establishing an environment ripe for the spread of cancer Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called "soil and seed" theory of 1889. New details that could help shed light on this hypothesis have been provided by a team of researchers from Weill Cornell Medical College, Memorial...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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