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Latest Breast cancer metastasis Stories

2012-04-25 09:43:34

Researchers say drug based on their discovery might target several tumor types A single gene that promotes initial development of the most common form of lung cancer and its lethal metastases has been identified by researchers at Mayo Clinic in Florida. Their study suggests other forms of cancer may also be driven by this gene, matrix metalloproteinase-10 (MMP-10). The study, published in the journal PLoS ONE on April 24, shows that MMP-10 is a growth factor secreted and then used by...

2012-04-24 09:48:46

UD research identifies a protein that regulates the creation of fat cells Biology Major Adam Reese may have found the key to keep fat cells from forming. The University of Delaware junior believes he has identified the trigger that turns a stem cell into a fat cell. Located on the surface of cells, the trigger, a protein called endoglin, regulates what type of cell an existing stem cell will become. Working in the biological science department's laboratory of cellular signaling and...

2012-04-10 10:56:42

Peroxiredoxin 2 protects tumor cells from oxidative stress and promotes their growth and proliferation in the lung Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that breast cancer cells that metastasize to the lung express a higher level of the protein peroxiredoxin 2 (PRDX2). The study suggests that the modulation of the levels of this protein could be a new therapeutic strategy to prevent lung metastases. The study results have been advanced in the...

2012-04-04 20:20:57

The new model may provide scientists with a better understanding of the disease and help with developing effective interventions Inflammatory breast cancer (IBC) is a very aggressive, often misunderstood type of cancer that is diagnosed more frequently in younger women compared with other types of breast cancer. The five-year survival rate is between 25 and 50 percent–significantly lower than the survival rate for other types of breast cancer. The reason for the poor prognosis is...

2012-03-16 09:40:43

A powerful new strategy for personalized anti-cancer therapy Researchers at the Kimmel Cancer Center at Jefferson have demonstrated for the first time that the metabolic biomarker MCT4 directly links clinical outcomes with a new model of tumor metabolism that has patients "feeding" their cancer cells. Their findings were published online March 15 in Cell Cycle. To validate the prognostic value of the biomarker, a research team led by Agnieszka K. Witkiewicz, M.D., Associate Professor of...

2012-03-15 16:56:52

American Cancer Society-Funded Research Reveals Molecule Called Cadherin-23 Could Play a Role in the Earliest Stages of Breast Cancer Rensselaer Polytechnic Institute Biologist Lee Ligon has found a previously unknown connection between breast cancer tumor cells and the surrounding healthy tissue. The results provide new information on the earliest stages of breast cancer metastasis. The results were published March 7, 2012, in the journal PLoS One, in a paper titled “ Cadherin-23...

2012-03-12 11:20:44

EDITOR'S PICK Restoring what's lost: uncovering how liver tissue regenerates The liver is unique among mammalian organs in its ability to regenerate after significant tissue damage or even partial surgical removal. Laurie DeLeve and her colleagues at the University of Southern California in Los Angeles wanted to better understand which cells are specifically responsible for driving liver regeneration. A specialized cell type, known as liver sinusoidal endothelial cells, has generally been...

2012-03-06 11:05:26

Discovered a mechanism explaining how tumor cells spread to nearby organs and structures, initiating metastasis Metastasis is responsible for 90% of deaths in patients with cancer. Understanding the mechanisms responsible for this process is one of the top goals of cancer research. The metastatic process involves a series of steps chained where the primary tumour invades surrounding tissues and ends spreading throughout the body. Ones of the first tissues undergoing metastasis are the...

2012-03-06 10:41:07

Silencing it impairs tumor growth, making ROR1 a potential therapeutic target A team of scientists at the University of California, San Diego Moores Cancer Center has identified a novel protein expressed by breast cancer cells — but not normal adult tissues — that could provide a new target for future anti-cancer drugs and treatments. Led by Thomas J. Kipps, MD, PhD, Evelyn and Edwin Tasch Chair in Cancer Research and Interim Director of the UC San Diego Moores Cancer...

2012-02-13 23:02:59

A new study reveals key factors that promote the spread of cancer to lymph nodes and provides a mechanism that explains how a common over-the-counter anti-inflammatory medication can reduce the spread of tumor cells through the lymphatic system. The research, published by Cell Press in the February 14 issue of the journal Cancer Cell, opens new avenues for the design of antimetastatic therapies. The lymphatic system consists of a network of vessels that carry lymphatic fluid from the body...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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