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Latest Breast cancer metastasis Stories

2011-02-16 16:50:32

A Massachusetts General Hospital (MGH) study has identified a new role for an important enzyme in preparing lung tissue for the development of metastases. Published in the early edition of Proceedings of the National Academy of Sciences, the report describes how focal adhesion kinase (FAK) is involved in producing areas of vascular leakiness in lung tissue "“ known to be part of the premetastatic process "“ and increases expression of a molecule that attracts cancer cells to...

2011-02-10 16:48:26

A small piece of genetic material stops the activity of an enzyme known to promote the spread of breast tumors to the brain, said a group of researchers at Baylor College of Medicine. "We have shown that the enzyme heparanase is an important mediator of brain metastasis (breast cancer spread to the brain)," said Dr. Dario Marchetti, lead author and professor of pathology and immunology, cell and molecular biology at BCM and member of the NCI-designated Dan L. Duncan Cancer Center at the...

2011-01-21 07:00:00

BUFFALO, N.Y., Jan. 21, 2011 /PRNewswire/ -- CureFAKtor Pharmaceuticals, LLC, a privately-held biopharmaceutical company focused on the research and development of Focal Adhesion Kinase (FAK) inhibitors for cancer, today presented research results at the American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium in San Francisco demonstrating that novel FAK inhibitors targeting the binding site of vascular endothelial growth factor receptor 3 (VEGFR-3) reduced the...

2011-01-19 13:29:00

CAMBRIDGE, Mass., Jan. 19, 2011 /PRNewswire/ -- Pervasis Therapeutics, Inc. today announced that the company is pursuing a matrix-embedded endothelial cell-based therapy (PVS-30200) to target and regulate cell stroma (the tumor environment or "ecosystem" that is comprised of various supporting cell types distinct from cancer cells) in order to prevent key processes that play a role in advancing solid tumor growth and metastasis (the spread of cancer cells to secondary locations). A...

2011-01-07 11:21:42

Scientists attached to VIB and K.U.Leuven have succeeded in decoding a potential new anti-cancer mechanism. The researchers discovered that normalizing abnormal tumor blood vessels through HRG (histidine-rich glycoprotein) prevents metastasis of tumor cells and enhances chemotherapy efficiency. In tumors, vessels formation is disturbed, leading to inefficient delivery of chemotherapeutic drugs and allowing cancer cells to escape to other parts of the body (metastasis). The normalization of...

2010-12-15 07:00:00

EMERYVILLE, Calif., Dec. 15, 2010 /PRNewswire/ -- Bionovo, Inc. (Nasdaq: BNVI) today announced the publication of a study entitled "CC3/TIP30 regulates metabolic adaptation of tumor cells to glucose limitation" in the journal Cell Cycle. The study describes the critical linkage between the expression of the protein CC3/TIP30 in cancer cells and their ability to adapt and survive in adverse conditions such as lack of glucose and other nutrients. Lack of CC3/TIP30 in a variety of human...

2010-12-13 06:04:34

(Ivanhoe Newswire) -- Researchers at Vanderbilt University Medical Center suggest that decreased expression of the protein alpha-2 integrin is predictive of tumor dissemination to distant sites and decreased survival in individuals with either breast or prostate cancer. The researchers first studied the role of the protein alpha-2-beta-1 integrin (which is composed of the alpha-2 integrin protein and the beta-1 integrin protein) in cancer initiation and progression using a clinically...

2010-12-07 12:35:12

Mary Zutter and colleagues, at Vanderbilt University Medical Center, Nashville, have generated data that lead them to suggest that decreased expression of the protein alpha-2 integrin is predictive of tumor dissemination to distant sites and decreased survival in individuals with either breast or prostate cancer. The researchers first studied the role of the protein alpha-2-beta-1 integrin (which is composed of the alpha-2 integrin protein and the beta-1 integrin protein) in cancer initiation...

2010-12-01 22:00:47

Noncancerous cells from primary site appear to facilitate tumor growth The process of metastasis requires that cancer cells traveling from a primary tumor find a hospitable environment in which to implant themselves and grow. A new study from Massachusetts General Hospital (MGH) Cancer Center researchers finds that circulating tumor cells prepare this environment by bringing along from their original site noncancerous cells that support tumor growth. The report has been published online in...

2010-11-10 01:00:00

LONDON, Nov. 10, 2010 /PRNewswire/ -- Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company") announces positive research findings demonstrating the ability of the Company's lead RNA interference (RNAi) drug candidate, Atu027, to prevent the formation of pulmonary metastasis in various animal models of cancer metastasis. Researchers showed that Atu027 inhibited multiple key biological processes that enable and contribute to the dissemination and formation of pulmonary metastases...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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