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Latest Breast cancer metastasis Stories

2010-09-30 09:13:27

(Ivanhoe Newswire) "“ Circulating tumor cells may create a new alternative and non-invasive source for biomarker assessment a new study shows. According to the National Cancer Institute, the major cause of mortality in patients with cancer is caused by tumor cells that escape from the primary tumor into the bloodstream and travel through the circulation to distant sites where they develop into secondary tumors. These are called circulating tumor cells or CTC, and they provide a link...

2010-06-01 14:27:10

On average, about five percent of total cancer research funding is spent on investigating metastases (the spread of cancer cells around the body) in Europe, yet metastatic disease is the direct or indirect cause of 90 percent of all cancer deaths, according to an editorial in the European Journal of Cancer (EJC). [1] The authors of the editorial, which introduces a special EJC issue on metastasis ("Stopping cancer in its tracks: metastasis as a therapeutic target"), highlight this discrepancy...

2010-06-01 13:42:57

UCSD researchers say novel enzyme may provide new target for future anti-cancer therapies Scientists at the University of California, San Diego have identified a previously unknown kinase that regulates cell proliferation, shape and migration, and may play a major role in the progression or metastasis of cancer cells. The research will be published in the May 31 online Early Edition of the Proceedings of the National Academy of Sciences. Richard L. Klemke, PhD, professor of pathology at the...

2010-05-14 11:22:30

Known as palladin, the 'architectural' protein helps regulate cell motility and migration Several years ago, scientists at Beth Israel Deaconess Medical Center (BIDMC) and other laboratories made a paradoxical discovery regarding the Akt molecular pathway, a popular target for cancer drug therapies. They discovered that while one Akt protein "“ Akt1 "“ was actively preventing cancer cells from spreading, another closely related family member "“ Akt2 "“ was actually...

2010-05-09 08:35:18

Gastric cancer is the most common malignant gastrointestinal cancer and accounts for 25% of cancer deaths. Nuclear matrix, a filamentous protein framework for eukaryotic cellular chromatin, closely relates to DNA duplication and transcription. Research on nuclear matrix proteins will provide insight into how tumors developed. A research article published on May 7, 2010 in the World Journal of Gastroenterology addresses this question. The research team from Xiamen University, China,...

2010-05-07 08:54:49

A new study of metastatic breast cancer shows that the number of circulating tumor cells patients have in their blood directly correlates with the length of their survival. Reported at the IMPAKT Breast Cancer Conference in Brussels, Belgium, the results have the potential to improve the delivery of personalized therapy to these patients. Circulating tumor cells --cancer cells found in a patient's bloodstream-- are detected in 50% to 80% of patients with metastatic breast cancer. Since 2004,...

2010-05-05 15:22:57

Researchers at the University of Kentucky Markey Cancer Center zero in on how breast tumor cells break free and start to spread Scientists at the University of Kentucky Markey Cancer Center have identified a key molecular mechanism in breast cancer that enables tumor cells to spread to adjacent or distant parts of the body in a process called metastasis. This finding opens the way to new lines of research aimed at developing treatments for metastatic breast cancer. The research, led by Peter...

2010-05-02 08:55:00

Current research suggests that tumor-secreted exosomes inhibit the immune response, enhancing tumor metastasis. The related report by Liu et al, "Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells," appears in the May 2010 issue of The American Journal of Pathology. The immune system plays a critical role in identifying and destroying tumor cells. Many tumors overcome this surveillance by inhibiting local immune responses, often leading to...

2010-04-13 13:44:09

4-protein complex provides new target for thwarting cancer migration, invasion The molecular machinery that switches on a gene known to cause breast cancer to spread and invade other organs has been identified by an international team led by scientists at The University of Texas M. D. Anderson Cancer Center. The paper was published Sunday in Nature Cell Biology's advanced online publication. The discovery provides a target-rich environment for development of drugs to thwart expression of the...

2010-03-29 09:25:53

One of the most intriguing questions in cancer research is what causes metastatic tumor migration, why some tumor cells manage to migrate to other parts of the body but others cells don't. International investigation conducted by Enrique Martín Blanco, CSIC researcher at the Institute of Biology of Barcelona, located in the Barcelona Science Park, reveals that cells make use of a natural mechanism for this. It happens to be a family of proteins that trigger cell migration in...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.