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Latest Breast cancer metastasis Stories

2009-08-26 09:29:09

Dr. Amanda Harvey and colleagues at Brunel University have demonstrated that the protein Brk plays a role in breast cancer progression and dissemination. Their report can be found in the September 2009 issue of the American Journal of Pathology.Breast cancer metastasis causes nearly 90% of the lethality among breast cancer patients. Non-metastatic breast cancer cells rely on interactions with other cells and the extracellular matrix to survive. Metastatic breast cancer cells must survive in...

2009-08-19 15:36:47

 Research led by Suresh Alahari, PhD, Associate Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has shown for the first time that a tiny piece of RNA appears to play a major role in the development of invasive breast cancer and identified a gene that appears to inhibit invasive breast cancer. The research is published in the August 21, 2009 issue of the Journal of Biological Chemistry.The LSUHSC researchers are the first to demonstrate that...

2009-08-19 12:24:25

Scientists from the U.S. Department of Energy's (DOE) Argonne National Laboratory and the University of Chicago's Brain Tumor Center have developed a way to target brain cancer cells using inorganic titanium dioxide nanoparticles bonded to soft biological material.Thousands of people die from malignant brain tumors every year, and the tumors are resistant to conventional therapies. This nano-bio technology may eventually provide an alternative form of therapy that targets only cancer cells...

2009-08-11 14:29:30

U.S. scientists say they've found cancer metastasis appears to rely on help from macrophages, potent immune system cells that usually defend against disease. Researchers led by Jeffrey Pollard at Yeshiva University's Albert Einstein College of Medicine analyzed the movement of breast cancer cells in mice. They discovered a distinct population of macrophages helps malignant cells locate at distant sites. Pollard and his colleagues said their finding offers a potentially useful new target for...

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2009-08-11 08:15:00

The deadliest part of the cancer process, metastasis, appears to rely on help from macrophages, potent immune system cells that usually defend vigorously against disease, researchers at Albert Einstein College of Medicine of Yeshiva University report.In a new study published online in PLoS ONE, Einstein cancer research specialist Jeffrey W. Pollard, Ph.D., and seven colleagues analyzed the movement of breast cancer cells in mice to show that a distinct population of macrophages helps...

2009-07-21 12:40:00

A team of researchers, at the Genome Institute of Singapore, has identified a new gene that seems to contribute to aggressive breast cancer behavior. As discussed in an accompanying commentary, by Gordon Mills and colleagues, the data generated in this study provide new insight into cellular processes underlying tumor cell proliferation and metastasis and identify potential new therapeutic targets.In the study, a new informatics approach was used to analyze microarray expression profiles of...

2009-07-16 13:52:37

An upcoming G&D paper reveals how two specific matrix metalloproteinase (MMP) proteins contribute to bone metastasis in advanced breast cancer "“ lending important new insight into the design of clinically useful small molecule inhibitors. The study was led by Dr. Yibin Kang in Princeton University in close collaboration with Dr. Joan Massagu© at MSKCC and Dr. Michael Reiss at the Cancer Institute of New Jersey. It will be published online ahead of print at...

2009-07-15 08:14:46

Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer, according to study results published in Clinical Cancer Research, a journal of the American Association for Cancer Research."This is the first study to measure circulating endothelial cells and endothelial progenitor cells in children with cancer, which can provide insight as to the biology of their tumor vessels," said researcher Françoise Farace, Ph.D.,...

2009-07-09 06:30:14

Your genetic make-up may determine whether or not cancer cells will spread, even years after treatment. A recent study has uncovered the genetic function that allows breast cancer cells to survive and spread to the bone even years after treatment. Researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) found breast cancer cells that get into the bone marrow can survive over time if they contain the gene product Src, which has been known to impact cell mobility, invasion and survival....

2009-07-06 13:40:53

Patients who survive an initial diagnosis of breast cancer often succumb to the disease years later when the cancer shows up in a different part of the body. Now, scientists have identified key signals that support the long term survival of breast cancer cells after they have spread to the bone marrow. The research, published by Cell Press in the July issue of the journal Cancer Cell, may lead to development of treatment strategies that decrease the likelihood of breast cancer recurrence in...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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