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Latest Breast cancer metastasis Stories

2009-07-06 13:37:12

New research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) sheds light on a genetic function that gives breast cancer cells the ability to survive and spread to the bone years after treatment has been administered. The findings support the study of therapies that target this survival capacity and force the death of latent breast cancer cells before they get a chance to metastasize, or spread "“ a problem that accounts for a majority of breast...

2009-07-01 12:19:59

 New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that linked the transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen...

2009-07-01 07:15:51

Researchers have identified a protein released by dying brain tumor cells that provides an effective way to gauge the effectiveness of a novel gene therapy treatment for brain cancer. The finding paves the way for a Phase 1 clinical trial expected to begin in late 2009. The two-pronged gene therapy was devised by scientists at the Cedars-Sinai Board of Governors Gene Therapeutics Research Institute.  It uses a harmless, genetically engineered virus to deliver a combination of...

2009-06-23 09:45:39

Researchers at Children's Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment. Their findings were published in the online Early Edition of the Proceedings of the National Academy of Sciences during the week of June 22.Metastasis"”the migration of cancer cells to other parts of the body"”is one of the leading causes of death from cancer, and there is no approved therapy for...

2009-06-17 12:58:41

A U.S. animal study suggests a new method to more accurately predict the likelihood of metastasis of breast cancer occurring in humans. Whitehead Institute for Biomedical Research scientists determined a low cellular level of a tiny fragment of RNA appears to increase the spread of breast cancer in mouse models of the disease. They said measuring levels of the so-called microRNA, which is also associated with metastatic breast cancer in humans, may help determine patient prognoses. Scott...

2009-06-16 08:00:17

A low cellular level of a tiny fragment of RNA appears to increase the spread of breast cancer in mouse models of the disease, according to researchers at Whitehead Institute for Biomedical Research.Measuring levels of this so-called microRNA, which is also associated with metastatic breast cancer in humans, may more accurately predict the likelihood of metastasis (which accounts for 90% of cancer-related deaths) and ultimately help determine patient prognoses.In the study, whose results are...

2009-06-09 09:24:42

As survival rates among some patients with cancer continue to rise, so does the spread of these cancers to the brain "“ as much as 40 percent of all diagnosed brain cancers are considered metastatic, having spread from a primary cancer elsewhere in the body.Now, scientists from The Scripps Research Institute have discovered a molecular mechanism that plays a pivotal role in controlling cancer growth in the brain. The discovery could provide a basis for potentially effective therapies...

2009-05-19 14:20:17

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer. In the Journal of Clinical Investigation, Harold (Hal) Moses, M.D., and colleagues report that this gene signature "“ which is associated with the transforming growth factor-beta (TGF-ÃŽ²) signaling pathway "“ correlates with reduced relapse-free survival in patients with breast cancer, especially in those with...

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2009-05-07 08:07:39

Researchers have discovered a trio of genes that could reveal why cancer cells move around in the body. Scientists said Wednesday that three genes found in mice may help explain how breast cancer cells overcome a natural barrier to get into the brain; two of the genes, COX2 and HB-EGF, have already been found to help cancer spread to the lungs. The team published the findings in the journal Nature. Researchers say the third gene, known as ST6GALNAC5, appears to make the outer coat of cancer...

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2009-04-16 15:44:50

By combining nanoparticles with a scorpion venom compound already being investigated for treating brain cancer, University of Washington researchers found they could cut the spread of cancerous cells by 98 percent, compared to 45 percent for the scorpion venom alone. "People talk about the treatment being more effective with nanoparticles but they don't know how much, maybe 5 percent or 10 percent," said Miqin Zhang, professor of materials science and engineering. "This was quite a surprise...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'