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Latest Burkholderia pseudomallei Stories

2014-02-14 08:25:55

Soligenix Initiates Medical Countermeasure Development of SGX943 PRINCETON, N.J., Feb. 14, 2014 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that the National Institute of Allergy and Infectious Diseases (NIAID) has...

2011-11-11 01:21:37

A key mechanism by which a bacterial pathogen causes the deadly tropical disease melioidosis has been discovered by an international team of scientists. The findings are published today in the journal Science and show how a toxin produced by the bacterium Burkholderia pseudomallei kills cells by preventing protein synthesis. The study, led by the University of Sheffield, paves the way for the development of novel therapies to combat the bacterium which infects millions of people across...

2011-10-03 22:55:33

Researchers in South East Asia have identified a novel mechanism whereby the organism Burkholderia pseudomallei — the cause of melioidosis, a neglected tropical infectious disease — develops resistance to ceftazidime, the standard antibiotic treatment. The change also makes the drug-resistant bacterium difficult to detect. B. pseudomallei is found in water and soil predominately in tropical climates and especially in South East Asia. It can infect both humans and animals and...

2010-12-23 18:02:01

Researchers at the University of Exeter have developed a new approach to studying potentially deadly disease-causing bacteria which could help speed up the process of finding vaccines. Dr Andrea Dowling, from the Centre for Ecology and Conservation at the university's Cornwall Campus, has pioneered a simple screen which can help isolate the virulent parts of the gene structures of pathogenic* bacteria. The screen allows researchers to simultaneously run thousands of tests where genes from the...

2010-09-15 08:00:00

CHICAGO, Sept. 15 /PRNewswire/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today participated in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference is being held in Boston, Massachusetts this week. (Logo:...

2010-08-17 08:00:00

CHICAGO, Aug. 17 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today announced that the Company will participate in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference will be held in Boston,...

2010-04-21 07:00:00

CHICAGO, April 21 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS) today announced positive results from an in vitro study assessing the efficacy of Restanza(TM) (cethromycin), its novel oral antibiotic, against 30 strains of Burkholderia pseudomallei, a serious, life-threatening bacterial pathogen. Restanza showed significant in vitro activity against clinical and environmental strains of B. pseudomallei as measured by minimal inhibitory...

2009-01-21 14:56:51

Australian scientists say they've discovered the pathogenic soil bacterium Burkholderia pseudomallei is influenced by land management practices. Researchers at the Menzies School of Health Research in Darwin, Australia, said they found the bacterium, which causes the emerging infectious disease melioidosis in humans and animals, is associated with land management changes such as livestock husbandry or residential gardening. These findings raise concerns that B. pseudomallei may spread due to...


Latest Burkholderia pseudomallei Reference Libraries

72_ee74f19d6ec18e594c4d7bc49406908f
2011-04-14 16:11:25

Burkholderia pseudomallei is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It causes the disease melioidosis in humans and animals and is also capable of infecting plants. The bacteria can from in a number of artificial environments. Optimal temperature is around 40°C in pH-neutral or slightly acidic environments. Most strains can ferment sugars without gas formation. The bacteria produces both exo and endo toxins although the role of these toxins has not been fully...

72_1f7a87cf9282ce45824475581068d25b
2011-04-14 16:00:01

Burkholderia mallei is a gram-negative bipolar aerobic bacterium. The human and animal pathogen causes Glanders. The Latin name of this disease gave name to the causative agent species. It is related to B. pseudomallei although the bacterium is nonmotile. The bacterium can be eliminated through numerous disinfectants including benzalkonium chloride, iodine, mercuric chloride, potassium permanganate, and ethanol. It can also be destroyed by heating or UV. Antibiotics have also been reported...

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Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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