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Latest Burkholderia Stories

2014-04-22 23:01:55

Computer model of pathogens paves way for new treatments. Charlottesville, VA (PRWEB) April 22, 2014 The two species of bacteria are genetically similar – both contagious, both drug resistant, both preying upon people with cystic fibrosis or weakened immune systems – yet they go about their sinister work very differently. There is much to be learned both from how they are alike and how they differ, and so researchers at the University of Virginia School of Medicine have recreated them...

2014-02-14 08:25:55

Soligenix Initiates Medical Countermeasure Development of SGX943 PRINCETON, N.J., Feb. 14, 2014 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that the National Institute of Allergy and Infectious Diseases (NIAID) has...

2011-11-11 01:21:37

A key mechanism by which a bacterial pathogen causes the deadly tropical disease melioidosis has been discovered by an international team of scientists. The findings are published today in the journal Science and show how a toxin produced by the bacterium Burkholderia pseudomallei kills cells by preventing protein synthesis. The study, led by the University of Sheffield, paves the way for the development of novel therapies to combat the bacterium which infects millions of people across...

2011-10-03 22:55:33

Researchers in South East Asia have identified a novel mechanism whereby the organism Burkholderia pseudomallei — the cause of melioidosis, a neglected tropical infectious disease — develops resistance to ceftazidime, the standard antibiotic treatment. The change also makes the drug-resistant bacterium difficult to detect. B. pseudomallei is found in water and soil predominately in tropical climates and especially in South East Asia. It can infect both humans and animals and...

2010-12-23 18:02:01

Researchers at the University of Exeter have developed a new approach to studying potentially deadly disease-causing bacteria which could help speed up the process of finding vaccines. Dr Andrea Dowling, from the Centre for Ecology and Conservation at the university's Cornwall Campus, has pioneered a simple screen which can help isolate the virulent parts of the gene structures of pathogenic* bacteria. The screen allows researchers to simultaneously run thousands of tests where genes from the...

2010-09-15 08:00:00

CHICAGO, Sept. 15 /PRNewswire/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today participated in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference is being held in Boston, Massachusetts this week. (Logo:...

2010-08-17 08:00:00

CHICAGO, Aug. 17 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today announced that the Company will participate in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference will be held in Boston,...

2010-04-21 07:00:00

CHICAGO, April 21 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS) today announced positive results from an in vitro study assessing the efficacy of Restanza(TM) (cethromycin), its novel oral antibiotic, against 30 strains of Burkholderia pseudomallei, a serious, life-threatening bacterial pathogen. Restanza showed significant in vitro activity against clinical and environmental strains of B. pseudomallei as measured by minimal inhibitory...


Latest Burkholderia Reference Libraries

72_ee74f19d6ec18e594c4d7bc49406908f
2011-04-14 16:11:25

Burkholderia pseudomallei is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It causes the disease melioidosis in humans and animals and is also capable of infecting plants. The bacteria can from in a number of artificial environments. Optimal temperature is around 40°C in pH-neutral or slightly acidic environments. Most strains can ferment sugars without gas formation. The bacteria produces both exo and endo toxins although the role of these toxins has not been fully...

72_1f7a87cf9282ce45824475581068d25b
2011-04-14 16:00:01

Burkholderia mallei is a gram-negative bipolar aerobic bacterium. The human and animal pathogen causes Glanders. The Latin name of this disease gave name to the causative agent species. It is related to B. pseudomallei although the bacterium is nonmotile. The bacterium can be eliminated through numerous disinfectants including benzalkonium chloride, iodine, mercuric chloride, potassium permanganate, and ethanol. It can also be destroyed by heating or UV. Antibiotics have also been reported...

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Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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