Latest Burkholderia Stories
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A key mechanism by which a bacterial pathogen causes the deadly tropical disease melioidosis has been discovered by an international team of scientists.
Researchers in South East Asia have identified a novel mechanism whereby the organism Burkholderia pseudomallei – the cause of melioidosis, a neglected tropical infectious disease – develops resistance to ceftazidime, the standard antibiotic treatment.
Researchers at the University of Exeter have developed a new approach to studying potentially deadly disease-causing bacteria which could help speed up the process of finding vaccines.
Burkholderia pseudomallei is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It causes the disease melioidosis in humans and animals and is also capable of infecting plants. The bacteria can from in a number of artificial environments. Optimal temperature is around 40Â°C in pH-neutral or slightly acidic environments. Most strains can ferment sugars without gas formation. The bacteria produces both exo and endo toxins although the role of these toxins has not been fully...
Burkholderia mallei is a gram-negative bipolar aerobic bacterium. The human and animal pathogen causes Glanders. The Latin name of this disease gave name to the causative agent species. It is related to B. pseudomallei although the bacterium is nonmotile. The bacterium can be eliminated through numerous disinfectants including benzalkonium chloride, iodine, mercuric chloride, potassium permanganate, and ethanol. It can also be destroyed by heating or UV. Antibiotics have also been reported...
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