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Latest Burkholderia Stories

2014-02-14 08:25:55

Soligenix Initiates Medical Countermeasure Development of SGX943 PRINCETON, N.J., Feb. 14, 2014 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat serious inflammatory diseases where there remains an unmet medical need, as well as developing several biodefense vaccines and therapeutics, announced today that the National Institute of Allergy and Infectious Diseases (NIAID) has...

2013-10-17 08:29:01

PRINCETON, N.J., Oct. 17, 2013 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense medical countermeasures where there remains an unmet medical need, announced today the formation of an international melioidosis Scientific Advisory Board (SAB). Comprised of clinicians and researchers from Australia, Thailand, Lao and The Netherlands with...

2012-12-18 16:24:20

SCOTTSDALE, Ariz., Dec. 18, 2012 /PRNewswire/ -- Matrixx Initiatives is voluntarily recalling 1 lot of Zicam® Extreme Congestion Relief nasal gel. The company is taking this step after finding a small amount of Burkholderia cepacia in a single sample of the product taken from the affected lot. The problem was detected during a routine review at the manufacturing facility. Tests on additional samples from the same lot have shown no evidence of the organism. (Photo:...

2011-11-11 01:21:37

A key mechanism by which a bacterial pathogen causes the deadly tropical disease melioidosis has been discovered by an international team of scientists. The findings are published today in the journal Science and show how a toxin produced by the bacterium Burkholderia pseudomallei kills cells by preventing protein synthesis. The study, led by the University of Sheffield, paves the way for the development of novel therapies to combat the bacterium which infects millions of people across...

2011-10-03 22:55:33

Researchers in South East Asia have identified a novel mechanism whereby the organism Burkholderia pseudomallei — the cause of melioidosis, a neglected tropical infectious disease — develops resistance to ceftazidime, the standard antibiotic treatment. The change also makes the drug-resistant bacterium difficult to detect. B. pseudomallei is found in water and soil predominately in tropical climates and especially in South East Asia. It can infect both humans and animals and...

2010-12-23 18:02:01

Researchers at the University of Exeter have developed a new approach to studying potentially deadly disease-causing bacteria which could help speed up the process of finding vaccines. Dr Andrea Dowling, from the Centre for Ecology and Conservation at the university's Cornwall Campus, has pioneered a simple screen which can help isolate the virulent parts of the gene structures of pathogenic* bacteria. The screen allows researchers to simultaneously run thousands of tests where genes from the...

2010-09-15 08:00:00

CHICAGO, Sept. 15 /PRNewswire/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today participated in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference is being held in Boston, Massachusetts this week. (Logo:...

2010-08-17 08:00:00

CHICAGO, Aug. 17 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, today announced that the Company will participate in the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (www.icaac.org). The International conference will be held in Boston,...

2010-04-21 07:00:00

CHICAGO, April 21 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (OTC Bulletin Board: ADLS) today announced positive results from an in vitro study assessing the efficacy of Restanza(TM) (cethromycin), its novel oral antibiotic, against 30 strains of Burkholderia pseudomallei, a serious, life-threatening bacterial pathogen. Restanza showed significant in vitro activity against clinical and environmental strains of B. pseudomallei as measured by minimal inhibitory...

2009-07-16 02:00:00

ZURICH, July 16 /PRNewswire/ -- An innovative treatment for infections of the respiratory tract in cystic fibrosis patients has received a second orphan drug designation in the US only weeks after a first designation was granted. The recent designation relates to Burkholderia cepacia pathogens that can cause lethal infections in cystic fibrosis patients. For Axentis Pharma AG of Zurich, Switzerland, both designations affirm the therapeutic potential of its product candidate...


Latest Burkholderia Reference Libraries

72_ee74f19d6ec18e594c4d7bc49406908f
2011-04-14 16:11:25

Burkholderia pseudomallei is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It causes the disease melioidosis in humans and animals and is also capable of infecting plants. The bacteria can from in a number of artificial environments. Optimal temperature is around 40°C in pH-neutral or slightly acidic environments. Most strains can ferment sugars without gas formation. The bacteria produces both exo and endo toxins although the role of these toxins has not been fully...

72_1f7a87cf9282ce45824475581068d25b
2011-04-14 16:00:01

Burkholderia mallei is a gram-negative bipolar aerobic bacterium. The human and animal pathogen causes Glanders. The Latin name of this disease gave name to the causative agent species. It is related to B. pseudomallei although the bacterium is nonmotile. The bacterium can be eliminated through numerous disinfectants including benzalkonium chloride, iodine, mercuric chloride, potassium permanganate, and ethanol. It can also be destroyed by heating or UV. Antibiotics have also been reported...

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