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Latest Burkholderia Stories

2009-07-16 02:00:00

ZURICH, July 16 /PRNewswire/ -- An innovative treatment for infections of the respiratory tract in cystic fibrosis patients has received a second orphan drug designation in the US only weeks after a first designation was granted. The recent designation relates to Burkholderia cepacia pathogens that can cause lethal infections in cystic fibrosis patients. For Axentis Pharma AG of Zurich, Switzerland, both designations affirm the therapeutic potential of its product candidate...

2009-03-18 09:14:15

The unexpected behaviour of a family of "superbugs" called the Burkholderia cepacia complex (Bcc) could have implications for the treatment of cystic fibrosis (CF) patients. CF patients produce large quantities of sticky mucus in their lungs that is difficult to expel and is easily infected by bacteria. A recent treatment for CF, inhalation of a sugar called mannitol, works by attracting moisture into the lungs. This thins the mucus making it easier to disperse. However, recent research by...

2009-01-21 14:56:51

Australian scientists say they've discovered the pathogenic soil bacterium Burkholderia pseudomallei is influenced by land management practices. Researchers at the Menzies School of Health Research in Darwin, Australia, said they found the bacterium, which causes the emerging infectious disease melioidosis in humans and animals, is associated with land management changes such as livestock husbandry or residential gardening. These findings raise concerns that B. pseudomallei may spread due to...

2009-01-21 09:14:57

Researchers from Menzies School of Health Research in Darwin, Australia have found that the soil bacterium Burkholderia pseudomallei, which causes the emerging infectious disease melioidosis in humans and animals, is associated with land management changes such as livestock husbandry or residential gardening. The study, published January 20 in the open-access journal PLoS Neglected Tropical Diseases, sheds light on the environmental occurrence of this bacterium in the soil.B. pseudomallei...

2008-10-22 15:00:30

Syntiron announced today that it was notified of a pending contract from the Defense Threat Reduction Agency (DTRA) to adapt Syntiron's licensed, patented vaccine technology to combat three major bioterrorism agents; Bacillus anthracis, Yersinia pestis, and Burkholderia pseudomallei. The amount of the contract is $3.8 million dollars. Bacillus anthracis: A non-contagious, potentially fatal disease, commonly referred to as anthrax, caused by breathing, eating, or absorbing through cuts in...

2006-11-22 15:00:59

Rockline Industries has recalled its store brand wet wipes after routine testing discovered the presence of Burkholderia cepacia (B. cepacia), a bacteria that can cause health problems for people already suffering from illness. The company said that the affected wet wipes, which have been sold in retail outlets such as Wal-Mart and Sam's Club, are likely to have a sour milk odor. As yet, there have been no reports of illness connected to the recall. The Centers for Disease Control and...

2006-08-17 19:41:32

NEW YORK (Reuters Health) - Two cases of melioidosis, an infectious disease caused by the bacterium Burkholderia pseudomallei that is rare in the US, were reported to the Florida Department of Health in 2005. Both patients had recently visited or arrived from Honduras, where the disease is endemic. One case resulted in paraplegia, and the other in death. In the CDC's Morbidity and Mortality Report for August 18, Dr. Aaron Kite-Powell, from the Broward County Health Department in...

2005-08-30 14:47:03

A team of biomedical researchers from Brandeis University and the University of Texas at Austin has determined the first 3-dimensional structure of an enzyme that may be pivotal in preventing certain bacterial infections in plants, animals and humans, according to a study published in the Proceedings of the National Academy of Sciences. The enzyme had already been shown in previous studies to significantly decrease soft rot in potato plants. The Brandeis and University of Texas team purified...

2004-11-28 03:00:22

On July 26, 2003, the Los Angeles County Department of Health Services (LACDHS) received a report that a local clinical laboratory had isolated from specimens Burkholderia pseudomallei, a category B biologic terrorism agent and the causative organism for melioidosis, which is endemic to certain tropical areas. Because laboratory workers had manipulated cultures of the organism, CDC was asked to assist in the subsequent investigation. This report summarizes the results of that investigation,...


Latest Burkholderia Reference Libraries

72_ee74f19d6ec18e594c4d7bc49406908f
2011-04-14 16:11:25

Burkholderia pseudomallei is a Gram-negative, bipolar, aerobic, motile rod-shaped bacterium. It causes the disease melioidosis in humans and animals and is also capable of infecting plants. The bacteria can from in a number of artificial environments. Optimal temperature is around 40°C in pH-neutral or slightly acidic environments. Most strains can ferment sugars without gas formation. The bacteria produces both exo and endo toxins although the role of these toxins has not been fully...

72_1f7a87cf9282ce45824475581068d25b
2011-04-14 16:00:01

Burkholderia mallei is a gram-negative bipolar aerobic bacterium. The human and animal pathogen causes Glanders. The Latin name of this disease gave name to the causative agent species. It is related to B. pseudomallei although the bacterium is nonmotile. The bacterium can be eliminated through numerous disinfectants including benzalkonium chloride, iodine, mercuric chloride, potassium permanganate, and ethanol. It can also be destroyed by heating or UV. Antibiotics have also been reported...

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Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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