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Latest Burnham Institute for Medical Research Stories

2009-06-05 09:24:16

 Scientists and engineers at UC Santa Barbara and other researchers have developed a nanoparticle that can attack plaque "“"“ a major cause of cardiovascular disease. The new development is described in a recent issue of the Proceedings of the National Academy of Sciences.The treatment is promising for the eventual development of therapies for cardiovascular disease, which is blamed for one third of the deaths in the United States each year. Atherosclerosis, which was the...

2009-04-13 15:28:10

New Protocol Quickly and Efficiently Differentiates Human Embryonic Stem Cells into Committed Neural Precursor Cells Investigators at the Burnham Institute for Medical Research (Burnham) have developed a protocol to rapidly differentiate human embryonic stem cells (hESCs) into neural progenitor cells that may be ideal for transplantation. The research, conducted by Alexei Terskikh, Ph.D., and colleagues, outlines a method to create these committed neural precursor cells (C-NPCs) that is...

2009-04-10 08:36:09

Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE). The study, which suggests a new approach to treating Type 1 diabetes, was published online on April 8 in the journal Transplantation.The team of scientists showed that after transplantation, the...

2009-03-24 07:30:00

SOUTH SAN FRANCISCO, Calif., March 24 /PRNewswire/ -- Catalyst Biosciences, Inc., a pioneer in the discovery and development of engineered proteases known as Alterase(TM) therapeutics, has appointed four new members to the company's Scientific Advisory Board (SAB). Robert J. Fletterick, Ph.D., David Ginsburg M.D., Guy S. Salvesen, Ph.D., and Gregory Stahl, Ph.D., join initial members Shaun Coughlin, M.D., Ph.D., Charles Craik, Ph.D., and James Wells, Ph.D. "We are pleased to welcome this...

2009-02-13 11:29:47

Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 diabetes. Their findings, published online January 9 in Experimental Diabetes Research, could provide a potential new target for therapy. Pamela Itkin-Ansari, Ph.D., assistant adjunct professor at the UC San Diego...

2009-01-13 07:01:00

LA JOLLA, Calif., Jan. 13 /PRNewswire/ -- Burnham Institute for Medical Research (Burnham) has signed an assay development and license agreement with Johnson & Johnson Pharmaceutical Research and Development, L.L.C. (J&JPRD). The agreement is Burnham's first broad-based partnership with a large pharmaceutical company. Under this multi-year agreement, Burnham will provide J&JPRD with access to high-throughput assay screening technologies to investigate certain drug targets for...

2009-01-12 13:30:00

SANTA MONICA, Calif., Jan. 12 /PRNewswire-USNewswire/ -- California's ethics commission has found that a member of the state stem cell agency's oversight board violated ethics rules when he intervened with agency staff members in attempt to win a research grant for his institution, the Burnham Institute for Medical Research. In a three-page warning letter for Burnham President John Reed, the Fair Political Practices Commission (FPPC) found that "Dr. Reed intended to influence a decision that...

2009-01-09 12:10:59

Researchers at the Burnham Institute for Medical Research (Burnham) have shown that search algorithms used in digital communications can help scientists identify effective multi-drug combinations. The study, led by Giovanni Paternostro, M.D., Ph.D., was published in the December 26, 2008, issue of PLoS Computational Biology.Using the stack sequential algorithm, which was developed for digital communications, the team of scientists searched for optimal drug combinations. This algorithm can...

2009-01-06 11:47:52

Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following DNA repair. Since Ddk is often deregulated in human cancers, this new understanding of its role in DNA damage control could help shape new cancer therapies. The research was published in the December 24 issue of Molecular Cell.Accurate DNA...

2008-12-02 07:00:00

ST. JOSEPH, Mich., Dec. 2 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that Burnham has become a certified GeneGo Center of Excellence. Burnham researchers will have institution-wide access to GeneGo's MetaCore data analysis suite, training and advanced support. The Burnham institute is a world-class biomedical research facility running multiple OMICs experimental studies throughout many departments, including research in cancer, stem cells, and...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.