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Latest C-Jun N-terminal kinases Stories

2013-01-11 13:03:12

Oxidative stress is a primary villain in a host of diseases that range from cancer and heart failure to Alzheimer´s disease, Amyotrophic Lateral Sclerosis and Parkinson´s disease. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that blocking the interaction of a critical enzyme may counteract the destruction of neurons associated with these neurodegenerative diseases, suggesting a potential new target for drug development. These...

2011-09-07 20:07:37

Inhibition of protein protects liver from acetaminophen toxicity in mice New research from the Keck School of Medicine of the University of Southern California (USC) may help prevent damage to the liver caused by drugs like acetaminophen and other stressors. Acetaminophen, more commonly known as Tylenol, helps relieve pain and reduce fever. The over-the-counter drug is a major ingredient in many cold and flu remedies as well as prescription painkillers like Percocet and Vicodin....

2011-07-29 14:53:55

Some compounds found in grapes help to protect skin cells from the sun's ultraviolet radiation, according to a study by researchers from the University of Barcelona and the CSIC (Spanish National Research Council). The study supports the use of grapes or grape derivatives in sun protection products. Ultraviolet (UV) rays emitted by the sun are the leading environmental cause of skin complaints, causing skin cancer, sunburn and solar erythema, as well as premature ageing of the dermis and...

2011-06-02 23:57:22

Discovery could provide new target for drug development against conditions including heart attack, stroke and Parkinson's disease Scientists from the Florida campus of The Scripps Research Institute have uncovered a potentially important new therapeutic target that could prevent stress-related cell death, a characteristic of neurodegenerative diseases such as Parkinson's, as well as heart attack and stroke. In the study, published recently in the journal ACS Chemical Biology, the scientists...

2010-07-15 02:40:09

Researchers reveal that JNK, a protein long known to help cells respond to stress, also controls cell cycle Put simply, a tumor is the result of out-of-control cell growth. To assure that the cell cycle "“ the cell's process of duplicating itself to make more cells "“ goes smoothly, a large network of proteins tells other proteins what to do and when to do it. When any of these layers of protein regulation fail, cell growth can get out of hand. A new study led by Ze'ev Ronai,...

2009-05-26 07:47:27

Rhabdomyosarcoma (RMS) is an aggressive muscle cancer that mostly affects children. The most common forms of RMS are embryonal rhabdomyosarcoma (ERMS) and alveolar rhabdomyosarcoma (ARMS). Although ARMS is less common than ERMS, it is associated with a much higher rate of mortality. A therapy tailored to the ARMS form of RMS is therefore badly needed. A team of researchers, at the Hospital for Sick Children, Toronto, and Monash Institute of Medical Research, Australia, has now provided hope...


Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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