Quantcast

Latest C57BL/6 Stories

Cocaine And Methamphetamine Response Differ Between Two Substrains Of 'Black 6' Laboratory Mouse
2013-12-20 06:45:36

Jackson Laboratory Researchers including Jackson Laboratory Professor Gary Churchill, Ph.D., have found a single nucleotide polymorphism (SNP) difference in cocaine and methamphetamine response between two substrains of the C57BL/6 or "Black 6" inbred laboratory mouse, pointing to Cyfip2 as a regulator of cocaine response with a possible role in addiction. The research team, led by Joseph Takahashi, Ph.D., of University of Texas Southwestern Medical Center and the Howard Hughes Medical...

2012-05-07 20:23:40

Candidate gene controls IGF1 levels, affecting both onset of reproductive maturity and longevity An intriguing clue to longevity lurks in the sexual maturation timetable of female mammals, Jackson Laboratory researchers and their collaborators report. Jackson researchers including Research Scientist Rong Yuan, Ph.D., had previously established that mouse strains with lower circulating levels of the hormone IGF1 at age six months live longer than other strains. In research published May...

2012-03-20 16:48:08

Researchers at the University of Cincinnati have found evidence that, in addition to affecting the heart, brain and nervous system, bisphenol A (BPA), could affect a mammal´s ability to reproduce by altering the structure of the uterus in ways that can progress to a potentially fatal infection. Infection and inflammation of the uterus, or pyometra, is most commonly seen in animals like dogs and cats but can also affect humans. It is a result of hormonal and structural changes in the...

2011-07-14 15:44:44

The Collaborative Cross (CC) represents a large collection of new inbred mouse strains created by the mouse genetics community aimed at revolutionizing the study of complex genetic traits and diseases. Derived from classical inbred strains and wild-derived strains, the CC captures nearly 90% of known genetic variation in laboratory mice, far surpassing more commonly used inbred strains. The CC is a tool to integrate studies of gene function and gene networks, allowing the prediction and...

2011-03-10 13:46:41

What happened to being "quiet as a mouse"? Researchers have recently shown that, rather than being the silent creatures of popular belief, mice emit ultrasonic calls in a variety of social contexts, and these calls have song-like characteristics. So if mice sing, where do they get their music? Are they born with the songs fully formed in their heads, or do they learn them from their peers? This question is of great interest to scientists as, while many organisms produce genetically regulated...

2010-09-03 18:06:08

Duke University Medical Center researchers have found two genes in mice which might help identify why some people are more susceptible than others to potentially deadly staph infections. The researchers uncovered important genetic clues that ultimately could help inform patient management and drug development. "If you know up front that a patient is at risk for developing an Staphylococcus aureus infection, then you will be better able to manage them clinically, give them preventive measures,...

940b65086436ad52596f062387076d751
2009-01-26 08:15:00

If you are a mouse on the chubby side, then eating less may help you live longer. For lean mice "“ and possibly for lean humans, the authors of a new study predict "“ the anti-aging strategy known as caloric restriction may be a pointless, frustrating and even dangerous exercise. "Today there are a lot of very healthy people who look like skeletons because they bought into this," said Raj Sohal, professor at the University of Southern California's School of Pharmacy. He and...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.