Latest Ca2+/calmodulin-dependent protein kinase Stories

2013-10-03 16:25:09

The stresses that come with aging, chemotherapy treatments, and environmental exposures all threaten fertility. But what if there were a way to preserve women's limited egg supply? Researchers reporting on studies conducted in frog and mouse eggs in the Cell Press journal Molecular Cell on October 3rd may have found a way. The findings come at an important time when many women are waiting longer and longer to have children, renewing interest in the development of strategies to preserve...

2013-09-30 15:04:25

Brett Smith for redOrbit.com - Your Universe Online While heart disease is a significant health problem among members of the general population, it is particularly prevalent among individuals with diabetes, who have four times the risk of others. New research published in the journal Nature may provide a window into the unique connection between blood sugar levels and heart problems. The study revealed a biochemical pathway that causes irregular heartbeats when blood sugar levels become...

Enzyme Could Explain Link Between Diabetes And Heart Attack Death
2013-02-16 08:22:59

redOrbit Staff & Wire Reports — Your Universe Online The over-activation of a vital heart enzyme leads to the death of pacemaker cells, abnormal heart rhythm, and an increased risk of sudden cardiovascular death in diabetic mice, researchers have discovered in a study that could shed new light on the relationship between the two ailments. More than eight percent of the U.S. population has diabetes, and heart attack is the primary cause of death in those individuals, according...

2011-03-21 13:10:52

You may remember the color of your loved one's eyes for years. But how? Scientists believe that long-term potentiation (LTP) "“ the long-lasting increase of signals across a connection between brain cells -- underlies our ability to remember over time and to learn, but how that happens is a central question in neuroscience. Researchers at Duke University Medical Center have found a cascade of signaling molecules that allows a usually very brief signal to last for tens of minutes,...

2010-03-11 09:07:54

Current drugs used to treat heart failure and arrhythmias (irregular heartbeat) have limited effectiveness and have side effects. New basic science findings from a University of Iowa study suggest a way that treatments could potentially be refined so that they work better and target only key heart-related mechanisms. The team, which included researchers from Vanderbilt University, showed in theory that it might be possible to use drugs that maintain the positive effects on heart function of a...

2009-12-05 00:44:19

Using a new mathematical model of heart cells, University of Iowa investigators have shown how activation of a critical enzyme, calmodulin kinase II (CaM kinase), disrupts the electrical activity of heart cells. The study, which also involved Columbia University, was published online Dec. 3 in the journal PLoS Computational Biology. "Recently, researchers have developed great interest in calmodulin kinase II as a critical regulator of the heart's response to injury. By targeting this enzyme's...

2009-06-17 13:16:39

 An overactive enzyme is behind a leaky calcium channel that plays a role in the development of atrial fibrillation, which is the most common cardiac arrhythmia that is responsible for a third of all strokes. However, it doesn't act alone, say researchers at Baylor College of Medicine. The findings can be found online in the current edition of the Journal of Clinical Investigation."When the heart pumps properly, the muscle contractions are regulated by waves of calcium. When the heart...

2008-10-24 07:50:00

Scientists have discovered a way to erase specific memories in mice while leaving others intact and not damaging the brain. Through manipulation of certain levels of an important protein in the brain, certain memories can be selectively deleted, according to a report published in the journal Neuron. "While memories are great teachers and obviously crucial for survival and adaptation, selectively removing incapacitating memories, such as traumatic war memories or an unwanted fear, could help...

Word of the Day
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'