Latest Cachexia Stories
Lee Rannals for redOrbit.com – Your Universe Online A study may be paving the way for finding ways to prevent muscle loss, obesity and diabetes. Researchers from Nanyang Technological University (NTU) found that by inhibiting a particular molecule produced naturally in the body, muscle loss due to aging or illness can be prevented. By blocking this same molecule, it triggers the body to go into a "fat-burning mode" which will fight obesity, and also treat the most common form of...
AUSTIN, Texas, Nov. 20, 2012 /PRNewswire/ -- XBiotech, a privately held biotechnology company, announced positive interim analysis results today from a Phase II study in patients receiving MABp1 to reduce restenosis after percutaneous revascularization of the Superficial Femoral Artery (SFA). Patients receiving MABp1 demonstrated a 58 percent reduction in Major Adverse Cardiovascular Events (MACE) and 60 percent longer patency in treated vessels compared to control patients. This...
AUSTIN, Texas, Oct. 29, 2012 /PRNewswire/ -- XBiotech, a privately held biotechnology company, announced positive interim analysis results today from a Phase II study using a True Human monoclonal antibody (MABp1) in patients with type 2 diabetes. Results from this study continue to reinforce the role of IL-1a as a master regulator of chronic inflammation in multiple disease states, and the therapeutic benefits of neutralizing antibodies produced from the XBiotech platform. The...
LUGANO, Switzerland and MELBOURNE, Australia, Oct. 15, 2012 /PRNewswire/ -- Melbourne biopharmaceutical company Specialised Therapeutics Australia (STA) has been granted exclusive commercialisation rights to a new drug for the treatment of NSCLC cachexia-anorexia. This condition is a serious multifactorial disorder which involves muscle wasting and metabolic impairment and commonly affects patients with advanced cancer. STA has reached agreement with Swiss pharmaceutical company...
NEW YORK, Oct. 5, 2012 /PRNewswire/ -- Ohr Pharmaceutical (OTCBB: OHRP), a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, announced today that Dr. Irach Taraporewala, Chief Executive Officer of Ohr Pharmaceutical, will be presenting at the 11(th) annual BIO Investor Forum taking place at The Palace Hotel in San Francisco on October 9-10, 2012. Dr. Taraporewala's presentation will include an overview of Ohr's clinical wet-AMD eye...
AUSTIN, Texas, Oct. 3, 2012 /PRNewswire/ -- XBiotech, a privately held biotechnology company, announced today that the company has been granted Fast Track designation for its anti-cachexia drug Xilonix. The Company's groundbreaking therapeutic antibody was shown in a previous clinical study at MD Anderson Cancer Center in Texas to stop or reverse cachexia in about a third of all advanced cancer patients treated. Anti-tumor and anti-cachexia effects were seen in many different types...
WICHITA, Kan., Sept. 25, 2012 /PRNewswire-USNewswire/ -- Inflammatory responses play roles at different stages of tumor development, including initiation, promotion, malignant conversion, invasion, and metastasis. The 'inflammation- cancer' connection is not restricted to increased risk for a subset of tumors. An inflammatory component is present in the microenvironment of most neoplastic tissues. High inflammatory levels appear to indicate increased cancer risk and poorer...
QUÉBEC CITY, Aug. 28, 2012 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: AEZS) (TSX: AEZ) (the "Company") today announced that a first patient has been recruited for a Phase 2A trial with its ghrelin agonist, AEZS-130 in patients with cancer cachexia. The study is conducted under a Cooperative Research and Development Agreement (CRADA) between Aeterna Zentaris and the Michael E. DeBakey Veterans Affairs Medical Center which is funding the study. Cachexia, characterized by...
Trial conducted through a Cooperative Research and Development Agreement QUÉBEC CITY, March 8, 2012 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: AEZS) (TSX: AEZ) (the "Company") today announced that the Michael E. DeBakey Veterans Affairs Medical Center, in Houston, Texas, has initiated a Phase 2A trial assessing the safety and efficacy of repeated doses of the Company's ghrelin agonist, AEZS-130 (macimorelin), in patients with cancer cachexia. The study is conducted under...
LUGANO, Switzerland, Dec. 7, 2011 /PRNewswire/ -- Helsinn, a Swiss-based pharmaceutical company, announced today that its US subsidiary, Helsinn Therapeutics Inc., has enrolled the first patient in ROMANA-3, the Company's 12-week safety extension study. The ROMANA-3 safety extension study is recruiting patients who have successfully completed ROMANA 1 or ROMANA 2, the Company's two phase III studies running in parallel that are evaluating anamorelin HCI for the treatment of...
