Latest Cancer Research Stories
Findings provide tools for better understanding of the human genome Chromosomes are strands of DNA that contain the blueprint of all living organisms. Humans have 23 pairs of chromosomes that instruct how genes are regulated during development of the human body. While scientists have developed an understanding of the one-dimensional structure of DNA, until today, little was known about how different parts of DNA are folded next to each other inside the nucleus. Using a powerful DNA...
Recent use for a year or more doubled the risk of invasive breast cancer The first large-scale U.S.-based study to evaluate the link between an injectable form of progestin-only birth control and breast cancer risk in young women has found that recent use of a year or more doubles the risk. The results of the study, led by breast cancer epidemiologist Christopher I. Li, M.D., Ph.D., of Fred Hutchinson Cancer Research Center, are published online ahead of the April 15 print issue of Cancer...
TORONTO, April 4, 2012 /PRNewswire/ - Trillium Therapeutics Inc., a privately-held biopharmaceutical company developing proprietary and innovative biologic therapies, today provided an update on its lead cancer program - a SIRPaFc fusion protein targeting the CD47 pathway. Trillium's SIRPaFc development candidate is a proprietary antibody-like fusion protein that blocks the activity of CD47, a molecule upregulated on many leukemias and solid tumors. CD47 binds to SIRPa on the...
CHICAGO, April 3, 2012 /PRNewswire/ -- CureFAKtor Pharmaceuticals, LLC, a privately-held biopharmaceutical company focused on the research and development of Focal Adhesion Kinase (FAK) inhibitors for cancer, today presented preclinical research results at the 2012 AACR Annual Meeting in Chicago, Illinois demonstrating that analogs of novel FAK inhibitor CFAK-C4 disrupted FAK-vascular endothelial growth factor receptor 3 (FAK-VEGFR3) interaction and inhibited pancreatic tumor...
Scientists may have discovered a new paradigm for immunotherapy against cancer by priming antibodies and T cells with cancer stem cells, according to a study published in Cancer Research, a journal of the American Association for Cancer Research. "This is a major breakthrough in immunotherapy research because we were able to use purified cancer stem cells to generate a vaccine, which strengthened the potency of antibodies and T cells that selectively targeted cancer stem cells," said Qiao...
CAMBRIDGE, Mass., April 2, 2012 /PRNewswire/ -- Good Start Genetics,(TM) Inc., an innovative molecular diagnostics company developing the new gold standard in carrier screening, today announced it completed the initial closing of a $14 million Series B Preferred Stock financing, which was led by existing investors OrbiMed Advisors, Safeguard Scientifics, Inc. (NYSE: SFE) and SV Life Sciences. Proceeds from this financing will be used to augment commercial efforts for the Company's...
CHARLOTTE, N.C., March 29, 2012 /PRNewswire/ -- Lineagen, Inc., an innovative molecular diagnostics company focused on complex, genetically linked disorders, today presented clinical utilization data for Lineagen's FirstStepDx. FirstStepDx is a comprehensive evaluation service that integrates highly advanced and comprehensive genetic testing for individuals with developmental delay (DD), intellectual disability (ID), and autism spectrum disorders (ASD) with personalized pre- and...
Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody, according to a new study from the Stanford University School of Medicine. The antibody works by masking a protein flag on cancer cells that protects them from macrophages and other cells in the immune system. The scientists achieved the findings with human breast, ovarian, colon, bladder, brain, liver and prostate cancer samples. It is the first antibody...
ROCKVILLE, Md., March 26, 2012 /PRNewswire/ -- BioHealth Innovation, Inc. (BHI), a new regional private-public partnership focusing on commercializing market-relevant biohealth innovations and increasing access to early-stage funding in Central Maryland, announced today its selection of Todd Chappell as the first Entrepreneur-in-Residence (EIR) for BHI at the National Institutes of Health (NIH) Office of Technology Transfer (OTT). Mr. Chappell, a venture capital-backed...
Dietary cadmium, a toxic metal widely dispersed in the environment and found in many farm fertilizers, may lead to an increased risk of breast cancer, according to a study published in Cancer Research, a journal of the American Association for Cancer Research. Cadmium occurs at low concentrations naturally, but scientists are concerned because contamination of farmland mainly due to atmospheric deposition and use of fertilizers leads to higher uptake in plants. "Because of a high...
