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Latest Capecitabine Stories

2008-06-30 09:01:51

Cytokinetics, Incorporated (NASDAQ: CYTK) announced today the results of a Phase Ib clinical trial designed to evaluate ispinesib in combination with capecitabine, an oral chemotherapy agent commonly used in the treatment of breast cancer. Ispinesib is a novel, small molecule inhibitor of kinesin spindle protein (KSP), a mitotic kinesin essential for proper cell division. Ispinesib, along with another KSP inhibitor, SB-743921 are chemically-distinct drug candidates that have arisen from a...

2008-06-25 06:00:56

By Claire Harrison Dr Seamus McAleer has been involved in trials of a new drug called Lapatinib at Belfast City Hospital which has offered women suffering a type of advanced breast cancer hope by slowing the disease. Around 1,000 women are diagnosed with breast cancer in Northern Ireland every year, with a quarter suffering the aggressive, fast- growing ErbB2-positive kind of the disease. For many women with this form of the disease who initially respond to treatment with Herceptin and...

2008-04-18 12:00:19

NUTLEY, N.J., April 18 /PRNewswire/ -- A novel biweekly dosing schedule of Xeloda(R) (capecitabine) enabled safe delivery of higher daily doses in the treatment of advanced breast cancer, according to an investigational study published in the April 10, 2008 issue of the Journal of Clinical Oncology. The data showed that a seven-days-on/seven-days-off (7-on/7-off) regimen, called "dose dense," was generally well-tolerated up to 2,000 mg twice daily (4,000 mg/day), providing a potential...

2007-01-23 15:00:58

Preliminary results show the combination of Xeloda plus Eloxatin, known as XELOX, to be equivalent to standard FOLFOX-4 chemotherapy treatment in terms of overall survival in first-line metastatic colorectal cancer patients. Given its dosing convenience advantage, XELOX has the potential to be a first-line treatment, provided it can be demonstrated as cost-effective. The 2,034 metastatic colorectal cancer patient study was originally designed to compare first-line XELOX (Roche/Chugai's...

2006-04-06 03:40:00

ZURICH -- Drugmaker Roche Holding AG said on Thursday its Xeloda oral chemotherapy was as effective as standard drugs in treating advanced stomach cancer, supporting analysts' views of higher sales potential. Roche said data from a Phase III study due to be presented at an American Society of Clinical Oncology meeting (ASCO) showed that Xeloda, when added to another chemotherapy called cisplatin, was at least as effective as the intravenous chemotherapy drug, 5-fluorouracil. Gastric cancer is...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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