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Last updated on April 24, 2014 at 1:21 EDT

Latest Carbohydrate metabolism Stories

2014-02-14 11:09:28

A protein that has been known until recently as part of a complex communications network within the cell also plays a direct role in regulating sugar metabolism, according to a new study published on-line in the journal Science Signaling (February 18, 2014). Cell growth and metabolism are tightly controlled processes in our cells. When these functions are disturbed, diseases such as cancer and diabetes occur. Mohamed Soliman, a PhD candidate at the Lunenfeld Tanenbaum Research Institute at...

2013-12-19 11:54:50

Berkeley Lab Researchers Show that Aerobic Glycolysis is a Cause of Malignancy Metabolism was lost in the shadows of cancer research for decades but has recently been reclaiming some of the spotlight. Now, Mina Bissell, Distinguished Scientist with Berkeley Lab’s Life Sciences Division and a leading authority on breast cancer, has shown that aerobic glycolysis – glucose metabolism in the presence of oxygen – is not the consequence of the cancerous activity of malignant cells but is...

2013-09-24 09:42:06

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function. Obesity and diabetes have reached epidemic levels and are responsible for increased morbidity and mortality throughout the world. Furthermore, the incidence of metabolic disease is significantly elevated in...

2013-01-23 10:20:01

The metabolic process which fuels the growth of many cancers has its origins in normal brain growth finds a new study published in BioMed Central's open access journal Cancer & Metabolism. Using knock-out mice the study shows that interfering with Hexokinase-2 (Hk2), an enzyme integral to glucose metabolism, reduces the aggressiveness of medulloblastoma, the most common malignant brain tumor in children, and allows long term survival of mice. Most cells only convert glucose to lactate...

Carbs Are The Fuel Of Choice At High Altitude
2012-12-07 13:13:53

Cell Press Mice living in the high-altitude, oxygen-starved environment of the Andean mountains survive those harsh conditions by fueling their muscles with carbohydrates. The findings, reported online on December 6 in Current Biology, a Cell Press publication, provide the first compelling evidence of a clear difference in energy metabolism between high- and low-altitude native mammals. "The high-altitude mice we examined in this study are a rare exception to a general exercise fuel use...

2012-04-02 12:55:48

Discovery may be a potential therapeutic for Type 2 diabetes In a finding that may challenge popular notions of body fat and health, researchers at Beth Israel Deaconess Medical Center (BIDMC) have shown how fat cells can protect the body against diabetes. The results may lead to a new therapeutic strategy for preventing and treating type 2 diabetes and obesity-related metabolic diseases, the authors say. In the last decade, several research groups have shown that fat cells in people...

2011-10-21 09:09:05

The condition tuberous sclerosis, due to mutation in one of two tumor suppressor genes, TSC1 or TSC2, causes the growth of non-malignant tumors throughout the body and skin. These tumors can be unsightly and cause serious damage to organs. Growth of tumors in the brain may cause seizures and in the kidney, liver or heart, tumors can disrupt normal function, to the extent of causing the organ to fail. New research published in BioMed Central's open access journal Cell and Bioscience shows that...

2011-10-03 05:48:54

(Ivanhoe Newswire) -- What do you know; two culprits turn out to be related!  Cancer and diabetes appear to have some biology in common.  A pathway that initially drew attention for its role in embryonic stem cells and cancer also influences the odds that mice develop or resist diabetes. According to a new study, mice with high levels of the cancer-promoting proteins become more sensitive to insulin and less prone to diabetes when on a high-fat diet. "This highlights the...

2011-09-29 22:53:02

Contrary to what you might think, cancer and diabetes appear to have some biology in common. According to a report in the September 30th issue of the Cell Press journal, Cell, a pathway that initially drew attention for its role in embryonic stem cells and cancer also influences the odds that mice develop or resist diabetes. Mice with high levels of the cancer-promoting proteins Lin28a or Lin28b become more sensitive to insulin and less prone to diabetes when on a high-fat diet, the new...

2011-09-13 11:49:42

Scientists from the Center for Applied Medical Research (CIMA) of the University of Navarra (Spain) have discovered that cardiotrophin 1, a protein synthesized by muscle cells and adipose tissue, has a marked effect on fat and glucose metabolism. "These new findings add to those we already know on this compound such the anti-ischemic and cytoprotective effects showed in acute liver damage and solid organ transplants gives CT-1 great possibilities to be developed in various serious...