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Latest Carbonic anhydrase inhibitors Stories

2013-11-18 08:30:03

Multiple Presentations Highlight Findings from Phase 3 Trial Investigating USL255 for Adjunctive Treatment of Epilepsy in Patients with Refractory Partial-Onset Seizures MAPLE GROVE, Minn., Nov. 18, 2013 /PRNewswire/ -- Upsher-Smith Laboratories, Inc. (Upsher-Smith), today announced that it will present new research from its epilepsy clinical development program for USL255 (extended-release topiramate) during the American Epilepsy Society's (AES) 67(th) Annual Meeting in Washington, DC,...

2012-07-13 10:43:05

Although acetazolamide is widely prescribed to prevent and treat acute mountain sickness (AMS), the appropriate dose at which it is effective and safe has not been clearly defined. A comprehensive review and meta-analysis of 24 studies comparing the efficacy and risks associated with increasing doses of acetazolamide is published in High Altitude Medicine & Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com). The article is available free...

2011-12-21 15:00:00

MOUNTAIN VIEW, Calif., Dec. 21, 2011 /PRNewswire/ -- VIVUS, Inc. (NASDAQ: VVUS) today announced topline preliminary results from its retrospective study of medical claims data on oral clefts (OC) associated with topiramate exposure in utero. The study, known as FORTRESS for Fetal Outcome Retrospective TopiRamate ExpoSure Study, identified 1,945 mother-infant dyads exposed to topiramate either alone (monotherapy) or in combination with other antiepileptic agents (polytherapy) in the...

2011-09-26 05:45:00

MOUNTAIN VIEW, Calif., Sept. 26, 2011 /PRNewswire/ -- VIVUS, Inc. (NASDAQ: VVUS) today announced that a poster authored by Dr. Mark W. Green, Director of the Center for Headache and Pain Medicine and Professor of Neurology and Anesthesiology at the Mount Sinai School of Medicine, will be presented at the American Neurological Association (ANA) Meeting in San Diego, CA. In addition to the topiramate exposure data previously reported, the results will include the rate of major congenital...

2011-07-20 05:45:00

MOUNTAIN VIEW, Calif., July 20, 2011 /PRNewswire/ -- VIVUS, Inc. (NASDAQ: VVUS) today announced that on August 31, 2011, during the late breaking poster session at the 29th International Epilepsy Congress (IEC) in Rome, Italy, Dr. Alison Pack, Associate Professor of Clinical Neurology, Department of Neurology, Columbia University Medical Center, will present the results of a retrospective study of medical claims data on oral clefts (OC) and major congenital malformations (MCMs) associated...

2011-06-10 00:00:31

Topiramate is a medication that's been used for the treatment of the seizures associated with epilepsy, and in recent years it has also been used to treat the symptoms of migraine headaches. The Consumer Justice Foundation hereby announces that it has provided new information regarding the potential effects of Topiramate on unborn children of mothers who have used Topiramate for migraine headaches and who were unaware of the potential Topiramate side effects. This information can be found...

2011-06-06 15:18:43

The drug topiramate can help people lose weight as long as they can tolerate the side effects, according to authors of a new study that reviewed the medical literature. Brazilian researchers will present the results Saturday at The Endocrine Society's 93rd Annual Meeting in Boston. Among more than 3,300 overweight or obese patients, those who took topiramate for at least four months lost 11.8 pounds more on average than individuals who took "dummy" pills, or placebo, found the meta-analysis,...

2010-12-06 09:21:00

MAPLE GROVE, Minn., Dec. 6, 2010 /PRNewswire/ -- Data presented yesterday showed that USL255, a novel extended-release (ER) formulation of topiramate, was associated with less fluctuation in topiramate plasma levels than immediate-release (IR) topiramate in healthy volunteers. These and other findings from the USL255 early development program were presented Sunday, Dec. 5, at the 64th annual American Epilepsy Society (AES) meeting in San Antonio, TX. USL255, developed by Upsher-Smith...

2010-11-09 08:00:00

MAPLE GROVE, Minn., Nov. 9, 2010 /PRNewswire/ -- Upsher-Smith Laboratories, Inc. today announced the addition of an open-label extension study to PREVAIL, its global Phase III clinical trial for USL255 (extended-release topiramate). An internally developed program for the adjunctive treatment of adult epilepsy patients with partial-onset seizures, USL255 is designed to provide convenient once-daily dosing and reduce fluctuations in topiramate blood levels observed with currently available...

2009-03-27 14:04:00

PRINCETON, N.J., March 27 /PRNewswire/ -- Zydus Pharmaceuticals announced today that it has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Topiramate Tablets USP, 25mg, 50mg, 100mg, and 200mg. This product is available for immediate shipment. Topiramate tablets are indicated as an initial monotherapy in patients 10 years old or older with partial onset or primary generalized tonic-clonic seizures. It is also...