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Last updated on April 20, 2014 at 8:28 EDT

Latest carcinogenesis Stories

2014-04-18 15:49:22

Studies carry implications for understanding cancer Johns Hopkins researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies: When a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them. The discovery sheds light on the tiny "environments" that stem cells occupy in animal bodies and may help explain how stem cells in tumors replenish themselves, the researchers report...

2014-04-11 12:07:26

A group of researchers in China and the US have successfully created a 3D model of a cancerous tumor using a 3D printer. The model, which consists of a scaffold of fibrous proteins coated in cervical cancer cells, has provided a realistic 3D representation of a tumor's environment and could help in the discovery of new drugs and cast new light on how tumors develop, grow and spread throughout the body. The results of the study have been published today, 11 April, in IOP Publishing's...

2014-04-11 11:57:29

Most breast cancers are treated by blocking their addictions, for example depriving estrogen-fueled tumors of estrogen. But what about breast cancers without these hormonal addictions? In so-called "triple negative" tumors the cancer's addiction remains a mystery, making this subtype difficult to treat. However, a University of Colorado Cancer Center study presented today at the American Association for Cancer Research (AACR) Annual Meeting 2014 showcased a new drug active against...

2014-04-10 14:53:02

In 10% of human tumors there is a family history of hereditary disease associated with mutations in identified genes. The best examples are the cases of polyps in the large intestine associated with the APC gene and breast cancer associated with BRCA1 and BRCA2 genes. In the remaining 90% of cases are believed to have an increased risk of developing cancer in relation to genetic variants less powerful but more often, for example, doubles the risk of having a tumor that lacks this small...

2014-04-09 23:31:47

Watch our Colon Health Educational Programming on PBS and major networks. Santa Rosa, CA (PRWEB) April 09, 2014 GI for Life, an innovative nutritional company focused on digestive health products is proud to announce the introduction of their first nationally televised program developed to inform viewers of the prevalence of colon disease, as well as introduce their cutting edge products designed to promote and maintain digestive and colon health. The program was produced by Outlook TV,...

2014-04-08 08:30:17

Patent provides protection until 2033 and complements Epizyme's issued composition of matter claims for EZH2 inhibitors CAMBRIDGE, Mass., April 8, 2014 /PRNewswire/ -- Epizyme, Inc. (NASDAQ: EPZM), a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, announced today that the U.S. Patent and Trademark Office has granted U.S. Patent No. 8,691,507 with claims that cover the identification of patients...

2014-04-07 16:10:23

A blood sample could one day be enough to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient's body and responses to treatment. Previous versions of the approach, which relies on monitoring levels of tumor DNA circulating in the blood, have required cumbersome and time-consuming steps to customize it to each patient or have not been sufficiently sensitive. Now, researchers at the Stanford University School of Medicine have devised a way to quickly bring...

2014-04-04 23:31:28

St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project finds TP53 gene is altered in nearly all osteosarcomas; results help explain how tumors withstand radiation therapy. Memphis, Tenn. (PRWEB) April 03, 2014 The St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role early in...

2014-04-03 12:29:26

HAIFA, Israel, April 3, 2014 /PRNewswire/ -- Novocure, a commercial stage oncology company, announced today that new, pre-clinical data demonstrating the anti-tumor effects of NovoTTF(TM) Therapy will be presented at the 2014 American Association for Cancer Research (AACR) in San Diego (April 5-9, 2014). The new study results show that ovarian cancer cells treated with Tumor Treating Fields (TTFields) exhibit abnormal chromosomal separation during cell division, reducing the viability of...

2014-04-03 11:21:51

Stowers team reports genome-wide analysis of genes that drive cell division in a multicellular organism In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells. This process, called mitosis, is visually stunning to observe under a microscope. Equally stunning to cell biologists are the preparatory steps cells take to ensure that the process occurs safely....