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Latest Cardiac muscle Stories

2011-04-11 15:30:47

Heart failure affects roughly six million Americans, yet treatment consists of either a heart transplant or the insertion of mechanical devices that assist the heart. This is unacceptable to Roberto Bolli, MD, Chief of the Division of Cardiovascular Medicine at the University of Louisville in Louisville, Ky., which is why he is on a mission to make cardiac stem cell treatment an option for all who must cope with the limitations of a failing heart. Dr. Bolli is conducting the groundbreaking...

2011-03-23 20:43:12

Myocardits is an inflammation of the heart muscles that is a major cause of heart failure in young patients. In some cases, the disease is caused by viral infection, but in other patients it is linked to an autoimmune attack on the heart muscle. There are few effective treatment options for myocarditis, in part because the molecular mechanisms that underlie the defect are poorly defined. In this paper, researchers led by Myra Lipes, at the Joslin Diabetes Center in Boston, Massachusetts, used...

2011-03-23 20:31:32

Joslin Diabetes Center research may point toward new ways to diagnose and treat heart disease in people with type 1 diabetes People with type 1 diabetes, whose insulin-producing cells have been destroyed by the body's own immune system, are particularly vulnerable to a form of inflammatory heart disease (myocarditis) caused by a different autoimmune reaction. Scientists at Joslin Diabetes Center have revealed the exact target of this other onslaught, taking a large step toward potential...

2011-03-17 21:02:25

Novel mechanistic approach to directly modulating muscle contractility may represent a promising strategy to treat systolic heart failure Cytokinetics, Incorporated (Nasdaq: CYTK) announced today the publication of preclinical research in the March 18, 2011 issue of the journal Science regarding the activation of cardiac myosin by an investigational drug candidate, omecamtiv mecarbil, and the potential therapeutic role that this novel mechanism may play for patients with systolic heart...

2011-03-02 09:09:31

(Ivanhoe Newswire) "“ UT Southwestern Medical Center research has shown that the mammalian newborn heart can heal itself completely. Researchers, working with mice, found that a portion of the heart removed during the first week after birth grew back wholly and correctly "“ as if nothing had happened. "This is an important step in our search for a cure for heart disease, the No. 1 killer in the developed world," Dr. Hesham Sadek, assistant professor of internal medicine and senior...

2011-02-28 22:08:49

New research in the FASEB Journal suggests that intraspecies communication exists on a cellular level, as demonstrated by rats communicating with human stem cells in the same genetic language If Dr. Doolittle is famous for talking to animals, then here's a story that might make him hold his tongue: According to new research published online in The FASEB Journal (http://www.fasebj.org), scientists have successfully fused human stem cells derived from subcutaneous adipose (fat) tissue with...

2011-02-25 12:50:47

American Heart Association Rapid Access Journal Report Study Highlights:     * A protein called fibronectin-EDA was linked to heart muscle damage after a heart attack in an animal study.    * Mice genetically altered to lack FN-EDA had less heart damage after a heart attack.    * Researchers suggest these findings hold potential for therapies to reduce or prevent heart muscle damage after a heart attack. Scientists have identified a protein that...

2011-02-09 23:30:06

Using skin cells from young patients who have a severe genetic heart defect, Stanford University School of Medicine scientists have generated beating heart cells that carry the same genetic mutation. The newly created human heart cells "” cardiomyocytes "” allowed the researchers for the first time to examine and characterize the disorder at the cellular level. In a study to be published online Feb. 9 in Nature, the investigators also report their identification of a promising...

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2011-02-08 08:00:00

Hibernating, it turns out, is much more complicated than one might think. Research published in the latest issue of the journal Physiological and Biochemical Zoology illustrates a complex series of changes that occur in grizzly bears' hearts as they hibernate. The changes guard against complications that could arise from greatly reduced activity. A grizzly hibernates five to six months of the year. During that time, its heart rate slows drastically from around 84 beats per minute when active...

2010-12-23 18:03:23

Suggests potential strategy for repairing injured hearts By tweaking a single gene, scientists have mimicked in sedentary mice the heart-strengthening effects of two weeks of endurance training, according to a report from Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center (BIDMC). The genetic manipulation spurred the animals' heart muscle cells -- called cardiomyocytes -- to proliferate and grow larger by an amount comparable to normal mice that swam for up to three hours a...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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