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Latest Cardiac muscle Stories

2010-10-08 14:38:44

Heart muscle cells do not normally replicate in adult tissue, but multiply with abandon during development. This is why the loss of heart muscle after a heart attack is so dire"”you can't grow enough new heart muscle to make up for the loss. A team of researchers at the University of Pennsylvania School of Medicine describe the interconnections between three-molecules that control fetal, heart-muscle-cell proliferation in a mouse model that will help cardiologists better understand the...

2010-10-06 17:32:26

Platelet derived growth factor (PDGF) plays role in heart regeneration In research that one day may lead to the discovery of how to regenerate tissue damaged by heart disease, investigators at Childrens Hospital Los Angeles have identified PDGF as a key factor in the proliferation and transformation of epicardial cells, one type of cell that surrounds heart muscle and contributes to vessels. The study was published online September 21 in advance of the publication of the Proceedings of the...

2010-09-24 13:42:32

Scientists Showcase Steps to Stop Unwanted Enlargement of the Heart Like a well-crafted football play designed to block the opposing team's offensive drive to the end zone, the body constantly executes complex "Ëœplays' or sequences of events to initiate, or block, different actions or functions. Scientists at the University of Rochester Medical Center recently discovered a potential molecular playbook for blocking cardiac hypertrophy, the unwanted enlargement of the heart and a...

2010-08-31 20:36:54

A study of triathletes published in the online edition and October issue of Radiology reveals that the heart adapts to triathlon training by working more efficiently. "To our knowledge, this is the first study using MRI to investigate effects of triathlon training on cardiac adaptations," said lead researcher Michael M. Lell, M.D., associate professor at the University of Erlangen-Nuremberg in Erlangen, Germany. Dr. Lell and colleagues conducted cardiac MRI on 26 professional male triathletes...

2010-08-31 10:03:40

(Ivanhoe Newswire) "“ A study of triathletes revealed that the heart adapts to triathlon training by working more efficiently. Triathlons are multi-sport events consisting of swimming, cycling and running various distances in succession. "To our knowledge, this is the first study using MRI to investigate effects of triathlon training on cardiac adaptations," lead researcher Michael M. Lell, M.D., associate professor at the University of Erlangen-Nuremberg in Erlangen, Germany, was...

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2010-08-30 19:53:01

The disruption of a structural component in heart muscle cells, which is associated with heart failure, appears to occur even before heart function starts to decline, according to a new study by researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine.The structure is a highly organized network of grooves in heart muscle membrane called T-tubules. This network is essential for transmitting electrical signals to the cell's interior where they are translated into...

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2010-08-10 07:55:00

These days people usually don't die from a heart attack. But the damage to heart muscle is irreversible, and most patients eventually succumb to congestive heart failure, the most common cause of death in developed countries. Stem cells now offer hope for achieving what the body can't do: mending broken hearts. Engineers and physicians at the University of Washington have built a scaffold that supports the growth and integration of stem cell-derived cardiac muscle cells. A description of the...

2010-08-05 16:39:11

Tissue regeneration a la salamanders and newts seems like it should be the stuff of science fiction. But it happens routinely. Why can't we mammals just re-grow a limb or churn out a few new heart muscle cells as needed? New research suggests there might be a very good reason: Restricting our cells' ability to pop in and out of the cell cycle at will "” a prerequisite for the cell division necessary to make new tissue "” reduces the chances that they'll run amok and form...

2010-08-05 16:36:07

In heart disease, cardiac muscle gradually dies off and, with little or no way to regenerate those cells, that can ultimately lead the heart to fail. But scientists reporting in the August 6th issue of Cell, a Cell Press publication, might have found a way to fix those losses. They've devised a three-ingredient molecular cocktail that transforms fibroblasts "“ structural cells that the heart is chock full of "“ directly into beating heart cells. "In the cardiac field, we've been...

2010-07-01 15:54:28

Scientists at the Stanford University School of Medicine have identified for the first time an enzyme that plays vital roles in both fetal heart development and in causing cardiac hypertrophy "” an enlargement of the heart "” in adults. The discovery could be used in the future to try to develop new treatments for heart disease. The study, which is to be published July 1 in Nature, was conducted by Ching-Pin Chang, MD, PhD, assistant professor of cardiovascular medicine, and his...


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