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Last updated on April 17, 2014 at 1:21 EDT

Latest Carolus Therapeutics Inc. Stories

2013-08-27 08:27:23

SAN DIEGO, Aug. 27, 2013 /PRNewswire/ -- Carolus Therapeutics, Inc. and The Alpha-1 Project, Inc. (TAP), a wholly-owned subsidiary of the Alpha-1 Foundation, today announced that they are collaborating to characterize human biological samples for the presence of the novel target, RANTES:PF4 heterodimer (the heteromer), a soluble protein complex that is secreted by activated platelets and implicated in many inflammation-related diseases, including genetic emphysema and COPD...

2012-01-20 07:00:00

SAN DIEGO, Jan. 20, 2012 /PRNewswire/ -- Carolus Therapeutics, Inc. today announced the publication of preclinical data showing that CT-2009 disrupts heteromers formed by the platelet-derived chemokines CCL5 (RANTES) and CXCL4, thereby preventing lung damage in multiple mouse models of acute lung injury (ALI). The study, published online on the website of the American Journal of Respiratory and Critical Care Medicine (AJRCCM), showed that CCL5-CXCL4 chemokine heteromers are...

2009-01-05 14:54:00

San Diego-Based Carolus Therapeutics Focuses on Discovery and Development of Anti-Inflammatory Drugs Based on Collaborators' Findings at RWTH Aachen University in Germany SAN DIEGO, Jan. 5 /PRNewswire/ -- Research published in Nature Medicine shows that the disruption of the interactions between two small signaling proteins called chemokines by a highly potent drug-like peptide inhibits the development of atherosclerosis in mice. San Diego-based Carolus Therapeutics Inc., which has...