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Latest Carolyn Bertozzi Stories

2012-11-01 10:13:42

Proteins are able to self-assemble into a wide range of highly ordered structures that feature a diverse array of properties. Through biomimicry — technological innovation inspired by nature — humans hope to emulate proteins and produce our own version of self-assembling molecules. A key to accomplishing this is understanding how protein-folding — a process critical to the form and function of a protein — is extended from individual proteins to complex assemblies....

2012-03-27 11:46:47

The traditional way of making medicines from ingredients mixed together in a factory may be joined by a new approach in which doctors administer the ingredients for a medicine separately to patients, and the ingredients combine to produce the medicine inside patients' bodies. That's one promise from an emerging new field of chemistry, according to the scientist who founded it barely a decade ago. Carolyn Bertozzi, Ph.D., spoke on the topic – bioorthogonal chemistry – here today...

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2010-05-31 07:32:46

Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley, have successfully attached imaging probes to glycans "“ the sugar molecules that are abundant on the surfaces of living cells "“ in the embryos of zebrafish less than seven hours after fertilization. Glycans are key regulators of the processes that guide cell development, and zebrafish are a top vertebrate model organism of...

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2010-01-20 08:56:48

For the first time, the widely used molecular synthesis technique known as click chemistry has been safely applied to a living organism. Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have crafted a unique copper-free version of click chemistry to create biomolecular probes for in vivo studies of live mice. Conventional click chemistry reactions require a copper catalyst that is toxic to cells and organisms. "We developed a...

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2009-03-05 10:12:10

Hybridized DNA is glue that sticks these cells together to resemble real tissue As synthetic biologists cram more and more genes into microbes to make genetically engineered organisms produce ever more complex drugs and chemicals, two University of California chemists have gone a step further. They have assembled different types of genetically engineered cells into synthetic microtissues that can perform functions such as secreting and responding to hormones, promising more complex biological...

2009-02-10 08:51:54

A new way to direct chemical modifications to specific sites on recombinant proteins "“ including the monoclonal antibodies so important in the pharmaceutical industry "“ has been developed by Carolyn Bertozzi and her colleagues at the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the University of California at Berkeley.Many therapeutic proteins, including insulin for diabetes, can be made in bacterial systems like Escherichia coli, but most protein...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.