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Latest Carolyn R. Bertozzi Stories

2012-03-27 11:46:47

The traditional way of making medicines from ingredients mixed together in a factory may be joined by a new approach in which doctors administer the ingredients for a medicine separately to patients, and the ingredients combine to produce the medicine inside patients' bodies. That's one promise from an emerging new field of chemistry, according to the scientist who founded it barely a decade ago. Carolyn Bertozzi, Ph.D., spoke on the topic – bioorthogonal chemistry – here today...

2012-03-26 09:52:12

More than a dozen symposia and other events at the American Chemical Society (ACS) 243rd National Meeting & Exposition are being sponsored or recommended by noted science communicator and ACS President Bassam Z. Shakhashiri, Ph.D. They range from a science outreach event for children at PETCO Park to news from an emerging field of chemistry that promises to produce medicines inside patients' bodies, as well as a symposium on communicating science to the public. Communicating science is...

2011-07-18 15:52:59

Scientists with Berkeley Lab and Einstein College of Medicine Extend Conventional Click Chemistry to Living Cells Biomolecular imaging can reveal a great deal of information about the inner workings of cells and one of the most attractive targets for imaging are glycans "“ sugars that are ubiquitous to living organisms and abundant on cell surfaces. Imaging a glycan requires that it be tagged or labeled. One of the best techniques for doing this is a technique called click chemistry....

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2010-05-31 07:32:46

Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley, have successfully attached imaging probes to glycans "“ the sugar molecules that are abundant on the surfaces of living cells "“ in the embryos of zebrafish less than seven hours after fertilization. Glycans are key regulators of the processes that guide cell development, and zebrafish are a top vertebrate model organism of...

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2010-01-20 08:56:48

For the first time, the widely used molecular synthesis technique known as click chemistry has been safely applied to a living organism. Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have crafted a unique copper-free version of click chemistry to create biomolecular probes for in vivo studies of live mice. Conventional click chemistry reactions require a copper catalyst that is toxic to cells and organisms. "We developed a...

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2009-03-05 10:12:10

Hybridized DNA is glue that sticks these cells together to resemble real tissue As synthetic biologists cram more and more genes into microbes to make genetically engineered organisms produce ever more complex drugs and chemicals, two University of California chemists have gone a step further. They have assembled different types of genetically engineered cells into synthetic microtissues that can perform functions such as secreting and responding to hormones, promising more complex biological...

2009-02-10 08:51:54

A new way to direct chemical modifications to specific sites on recombinant proteins "“ including the monoclonal antibodies so important in the pharmaceutical industry "“ has been developed by Carolyn Bertozzi and her colleagues at the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the University of California at Berkeley.Many therapeutic proteins, including insulin for diabetes, can be made in bacterial systems like Escherichia coli, but most protein...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.