Quantcast

Latest Caspase Stories

2014-05-07 08:45:28

A new study led by scientists at the University of Pennsylvania School of Veterinary Medicine has painted a clearer picture of the delicate arms race between the human immune system and a pathogen that seeks to infect and kill human cells. The research explores the strategies by which the bacterial pathogen Yersinia, responsible for causing plague and gastrointestinal infections, tries to outsmart immune cell responses and looks at the tactics used by the immune system to fight back....

2014-04-03 10:41:19

Findings may help develop targeted drug interventions and fight cancer and neurodegenerative diseases The molecular details of how zinc, an essential trace element of human metabolism, interacts with the enzyme caspase-3, which is central to apoptosis or cell death, have been elucidated in a new study led by researchers at Virginia Commonwealth University. The study is featured on the cover of the April issue of the journal Angewandte Chemie’s International Edition. Dysregulation of...

2013-11-19 12:37:11

Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer. The caspase-2 gene is related to a family of proteins that are essential for the self-destruction of cells in the body, a process known as apoptosis. Caspase-2 was first discovered almost 20 years ago by Professor Sharad Kumar, Co-Director of the Centre for Cancer Biology within SA Pathology, Affiliate Professor in the University of Adelaide's schools of...

2013-10-08 13:25:02

Mechanism meant to maintain efficiency of brain network involved in neurodegenerative disease Scientists at the Montreal Neurological Institute and Hospital-The Neuro, McGill University, have made important discoveries about a cellular process that occurs during normal brain development and may play an important role in neurodegenerative diseases. The study’s findings, published in Cell Reports, a leading scientific journal, point to new pathways and targets for novel therapies for...

2013-03-18 20:57:34

Results showing the same signaling enzymes can trigger two different processes in the cell sound a warning to biomedical researchers Stroke, heart attacks and numerous other common disorders result in a massive destruction of cells and tissues called necrosis. It´s a violent event: As each cell dies, its membrane ruptures, releasing substances that trigger inflammation, which in turn can cause more cellular necrosis. A new Weizmann Institute study may help develop targeted therapies...

2012-07-20 01:52:04

The research provides insights into programmed cell death and opens door to new approaches to cancer treatment Scientists at The Scripps Research Institute have simultaneously mapped two of the most important types of protein-modification in cells, revealing their extensive cooperation during an essential cellular process. Phosphorylation, the attachment of a phosphate group to a protein, and proteolysis, the cleavage of a protein, had almost always been studied independently. The new...

2012-05-02 13:22:17

Diseases and injuries trigger warning signals in our cells. As a result, genes are expressed and proteins produced, modified or degraded to adapt to the external danger and to protect the organism. In order to be able to produce a particular protein, the corresponding DNA segment, the gene, needs to be expressed and translated. The DNA is localized in the cell nucleus, and exists as a long string that is coiled and bound by proteins. ARTD1 is one such protein, and therefore has the potential...

2012-01-24 21:49:04

Glioblastoma, a lethal brain cancer, is one of the most resistant to available therapies and patients typically live approximately 15 months. Previous research has focused on the activation of the apoptosis, or cell death, pathway using therapeutic agents such as tumor necrosis factor-related apoptosis-inducing ligand (TRAIL); however, the vast majority of these experiments have been stymied by resistance. "Scientists in this field have been hoping to treat this cancer with this new...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
Related