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Latest Catecholamines Stories

2012-01-18 21:25:35

New research shows how neurons interact and could lead to new treatment for addiction Harvard scientists have developed the fullest picture yet of how neurons in the brain interact to reinforce behaviors ranging from learning to drug use, a finding that might open the door to possible breakthroughs in the treatment of addiction. The finding is the result of a year-long effort by a team of researchers led by associate professor of Molecular and Cellular Biology Naoshige Uchida to examine...

2011-12-21 22:46:41

A brain cell type found where habits are formed and movement is controlled has receptors that work like computer processors to translate regular activities into habits, researchers report. "Habits, for better or worse, basically define who we are," said Dr. Joe Z. Tsien, Co-Director of the Brain & Behavior Discovery Institute at Georgia Health Sciences University. Habits also provide mental freedom and flexibility by enabling many activities to be on autopilot while the brain focuses...

2011-12-13 22:52:18

Researchers convert astrocytes directly into dopamine-producing nerve cells of the midbrain In efforts to find new treatments for Parkinson´s Disease (PD), researchers from the Perelman School of Medicine at the University of Pennsylvania have directly reprogrammed astrocytes, the most plentiful cell type in the central nervous system, into dopamine-producing neurons. PD is marked by the degeneration of dopaminergic neurons in the midbrain. Dopamine is a brain chemical important in...

2011-11-28 15:11:39

Beta blockers prevent the negative effects of stress Stressed people fall into habits and their behavior is not goal-directed. That the neurotransmitter norepinephrine plays a decisive role here is now reported in the Journal of Neuroscience by scientists from Bochum led by Dr. Lars Schwabe (RUB Faculty of Psychology). If the effect of norepinephrine is stopped by beta blockers, the stress effect does not occur. "The results may be important for addictive behaviors, where stress is a key...

Image 1 - Worms May Hold Key To Identifying Drugs For Parkinson's Disease
2011-11-11 10:40:33

[ Watch the Video ] Test is based on the difficulty that these parkinsonian C. elegans worms have in switching from swimming to crawling Researchers at The University of Texas at Austin have devised a simple test, using dopamine-deficient worms, for identifying drugs that may help people with Parkinson's disease. The worms are able to evaluate as many as 1,000 potential drugs a year. The researchers have received federal funding that could increase that to one million drug tests a...

2011-10-31 10:11:38

A research team led by investigators at the Virginia Tech Carilion Research Institute has demonstrated the first rapid measurements of dopamine release in a human brain and provided preliminary evidence that the neurotransmitter can be tracked in its movement between brain cells while a subject expresses decision-making behavior. "In an experiment where we measured dopamine release while a subject made investment decisions in a stock market trading game, we showed that dopamine tracks...

2011-09-12 05:14:05

(Ivanhoe Newswire) — Dopamine is more than just for pleasure!  The lack of the brain chemical dopamine can rewire the interaction between two groups of brain cells and lead to symptoms of Parkinson´s disease. The discovery, made by Anatol Kreitzer, PhD, a scientist at Gladstone Institute, identified how the loss of dopamine alters the wiring of a small group of brain cells, kicking off a chain of events that eventually leads to difficulties controlling movement–a...

2011-08-31 12:44:08

"Our data indicate that the brain becomes hypersensitive to rewards when this co-signaling of glutamate and dopamine does not function. Lower doses than normal are enough to increase the propensity to ingest the substance, and this is true of both sugar and cocaine," says Ã…sa Mackenzie, associate professor of neuroscience at Uppsala University and the researcher who led the study. Addiction disorders are a major social problem, and we lack sufficient knowledge of how they...

2011-07-12 12:36:36

New animal research demonstrates gut hormone-induced changes in dopamine release New research findings to be presented at the upcoming annual meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that ghrelin, a natural gut hormone that stimulates feeding, also modulates the ability of tasty food and food-related cues to alter dopamine levels within the striatum, a critical component of the...

2011-04-08 15:46:05

A study of the salamander brain has led researchers at Karolinska Institutet to discover a hitherto unknown function of the neurotransmitter dopamine. In an article published in the prestigious scientific journal Cell Stem Cell they show how in acting as a kind of switch for stem cells, dopamine controls the formation of new neurons in the adult brain. Their findings may one day contribute to new treatments for neurodegenerative diseases, such as Parkinson's. The study was conducted using...