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Last updated on April 24, 2014 at 21:24 EDT

Latest Causes of schizophrenia Stories

Mental Illness Gene Treatment Schizophrenia
2013-07-16 09:13:45

Rebekah Eliason for redOrbit.com - Your Universe Online A new study involving brain impaired mice has the potential to improve therapy for people suffering from schizophrenia and major depressive disorder. While further research is necessary, this discovery is already being heralded as a major step toward understanding a variety of mental illnesses. The brain's prefrontal cortex, located in the anterior section of the frontal lobes, is associated with executive functions that help...

2013-07-16 08:30:52

TORONTO, July 16, 2013 /CNW/ - Scientists from the Centre for Addiction and Mental Health (CAMH) have discovered rare genetic changes that may be responsible for the onset of schizophrenia. Several of these same genetic lesions had previously been found to have causal links to autism spectrum disorder (ASD). This discovery gives new support to the notion that multiple rare genetic changes may contribute to schizophrenia and other brain disorders. This discovery also suggests...

2013-07-10 15:18:26

From a new study in Biological Psychiatry Many people with schizophrenia have marked problems with motivation, failing to initiate and persist in goal-directed behavior. These negative symptoms of schizophrenia can be disabling and prevent individuals from realizing their potential. For many years it was thought this was due to an inability to experience pleasure associated with successful goal attainment. However, recent laboratory studies have shown that hedonic experience is actually...

2013-04-18 21:46:09

Implications for early diagnosis and new treatment strategies An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center (CUMC) published in the current issue of Neuron. The findings suggest 1) a potential diagnostic tool for identifying those at risk for schizophrenia and 2) a possible glutamate-limiting treatment strategy to prevent or slow...

2013-04-10 16:40:49

Multiple genes contribute to risk for schizophrenia and appear to function in pathways related to transmission of signals in the brain and immunity, according to an international study led by Virginia Commonwealth University School of Pharmacy researchers. By better understanding the molecular and biological mechanisms involved with schizophrenia, scientists hope to use this new genetic information to one day develop and design drugs that are more efficacious and have fewer side effects....

2013-03-25 10:28:49

Research from the University of North Carolina has shown that children at risk of developing schizophrenia have brains that function differently than those not at risk. Brain scans of children who have parents or siblings with the illness reveal a neural circuitry that is hyperactivated or stressed by tasks that peers with no family history of the illness seem to handle with ease. Because these differences in brain functioning appear before neuropsychiatric symptoms such as trouble...

2013-03-13 15:27:30

Gamma-aminobutyric acid (GABA) deficits have been implicated in schizophrenia and depression. In schizophrenia, deficits have been particularly well-described for a subtype of GABA neuron, the parvalbumin fast-spiking interneurons. The activity of these neurons is critical for proper cognitive and emotional functioning. It now appears that parvalbumin neurons are particularly vulnerable to oxidative stress, a factor that may emerge commonly in development, particularly in the context of...

2013-03-08 00:22:52

Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections. Numerous findings in brain imaging studies describe the changes in brain structure and function associated with schizophrenia as emerging early in the course of the disorder. Some early brain imaging studies even found little or no evidence of progression of...

2013-03-05 11:43:26

Some of the dramatic differences seen among patients with schizophrenia may be explained by a single gene that regulates a group of other schizophrenia risk genes. These findings appear in a new imaging-genetics study from the Centre for Addiction and Mental Health (CAMH). The study revealed that people with schizophrenia who had a particular version of the microRNA-137 gene (or MIR137), tended to develop the illness at a younger age and had distinct brain features — both associated...

2013-02-19 15:09:53

Findings could help in early detection and intervention for people with the illness A study of eye movements in schizophrenia patients provides new evidence of impaired reading fluency in individuals with the mental illness. The findings, by researchers at McGill University in Montreal, could open avenues to earlier detection and intervention for people with the illness. While schizophrenia patients are known to have abnormalities in language and in eye movements, until recently...