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Latest Causes of schizophrenia Stories

2010-05-10 16:36:00

-- Study Finds Deletions and Repeats in DNA Sequences -- PHILADELPHIA, May 10 /PRNewswire-USNewswire/ -- By analyzing the genomes of patients with schizophrenia, genetics researchers have discovered numerous copy number variations -- deletions or duplications of DNA sequences -- that increase the risk of developing schizophrenia. Significantly, many of these variations occur in genes that affect signaling among brain cells. "When we compared the genomes of patients with schizophrenia to...

2010-05-10 15:42:03

Study finds deletions and repeats in DNA sequences By analyzing the genomes of patients with schizophrenia, genetics researchers have discovered numerous copy number variations"”deletions or duplications of DNA sequences"”that increase the risk of developing schizophrenia. Significantly, many of these variations occur in genes that affect signaling among brain cells. "When we compared the genomes of patients with schizophrenia to those of healthy subjects, we found variations in...

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2010-03-31 14:49:51

Like patients, engineered mice falter at working memory tasks The strongest known recurrent genetic cause of schizophrenia impairs communications between the brain's decision-making and memory hubs, resulting in working memory deficits, according to a study in mice. "For the first time, we have a powerful animal model that shows us how genetics affects brain circuitry, at the level of single neurons, to produce a learning and memory deficit linked to schizophrenia," explained Thomas R. Insel,...

2010-03-31 13:42:22

NEW YORK, NY "“ In what may provide the most compelling evidence to date, researchers at Columbia University Medical Center have illuminated how a genetic variant may lead to schizophrenia by causing a disruption in communication between the hippocampus and prefrontal cortex regions of the brain, areas believed to be responsible for carrying out working memory. Findings are published in the current online edition of Nature. This discovery coincides with the 15th anniversary of the first...

2010-03-11 08:54:48

In one of the first such studies involving human patients with schizophrenia, researchers at UC Davis have provided evidence that deficits in a brain chemical may be responsible for some of the debilitating cognitive deficits "” poor attention, memory and problem-solving abilities "” that accompany the delusions and hallucinations that are the hallmarks of the disorder. The study, published online March 10 in the Journal of Neuroscience, suggests an important avenue of inquiry for...

2010-03-02 08:24:13

Gene network-based analysis reveals unexpected results The underlying causes of the debilitating psychiatric disorder schizophrenia remain poorly understood. In a new study published online in Genome Research March 2, 2010, however, scientists report that a powerful gene network analysis has revealed surprising new insights into how gene regulation and age play a role in schizophrenia. Researchers are actively working to identify the direct cause of schizophrenia, likely rooted in...

2010-03-01 15:41:04

Offspring of two parents with schizophrenia or bipolar disorder appear more likely to develop the same illness or another psychiatric condition than those with only one parent with psychiatric illness, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The offspring of two parents with psychiatric illness represent an extremely high-risk group, according to background information in the article. Studying these children permits...

2010-02-24 14:32:52

Schizophrenia is an incredibly complex and profoundly debilitating disorder that typically manifests in early adulthood but is thought to arise, at least in part, from pathological disturbances occurring during very early brain development. Now, a new study published by Cell Press in the February 25 issue of the journal Neuron, manipulates a known schizophrenia susceptibility gene in the brains of fetal mice to begin to unravel the complex link between prenatal brain development and...

2010-02-01 18:27:19

Potentially beneficial brain changes (an increase in the volume of an area known as the hippocampus) occur in response to exercise both in patients with schizophrenia and healthy controls, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The findings suggest that the brain retains some plasticity, or ability to adapt, even in those with psychotic disorders. Schizophrenia is known to be associated with a reduced volume in the...

2010-01-28 12:44:55

New TAU study shows early intervention could prevent mind altering disorder The onset of schizophrenia is not easy to predict. Although it is associated with as many as 14 genes in the human genome, the prior presence of schizophrenia in the family is not enough to determine whether one will succumb to the mind-altering condition. The disease also has a significant environmental link. According to Prof. Ina Weiner of Tel Aviv University's Department of Psychology, the developmental disorder,...


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bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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