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Latest CD4 Stories

2008-10-28 18:00:28

WASHINGTON and RICHMOND, Calif., Oct. 28 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. announced today the presentation of data demonstrating that human CD4 T-cells can be made permanently resistant to HIV infection by treatment with zinc finger DNA-binding protein nucleases (ZFN(TM)) resulting in an increase in CD4 T-cell counts and a reduction in viral load in an animal model of HIV infection. The presentation, entitled, "Establishment of HIV Resistant CD4 T-cells Using Engineered...

2008-10-27 06:00:07

By Steve Sternberg WASHINGTON -- A new analysis of the best time to begin HIV treatment found that starting early sharply improves survival, doctors said Sunday. Doctors say the new evidence is certain to prompt many doctors to change the way they treat patients, and to prompt health officials to begin examining the evidence underlying guidelines for treating the AIDS virus. The study of 8,374 patients in the USA and Canada showed that those treated later in the course of HIV infection...

2008-09-22 18:00:34

A simple test given to HIV/AIDS patients in southern Africa could extend their lives by nearly a year and save health-care costs at the same time, according to a new study by researchers at the Stanford University School of Medicine and the Palo Alto Veterans Affairs Health Care System. The technique, known as the CD4 test, would be particularly valuable if it were given to patients early in their disease, before they became ill with an AIDS-related infection, the researchers found. Use...

2008-08-05 09:01:31

CAMBRIDGE, Mass., Aug. 5 /PRNewswire/ -- Tolerx, Inc., a biopharmaceutical company engaged in the discovery and development of novel therapies for the treatment of immune-mediated diseases, announced today that Genentech, a collaborator, has moved a modified version of TRX1, MTRX1011A, an anti-CD4 monoclonal antibody, into a phase 1 clinical trial that has begun enrolling patients. The clinical trial is evaluating the safety and tolerability of both single and multiple doses of MTRX1011A....

2008-07-25 18:00:00

Reducing stress can bolster the immune system in human immunodeficiency virus, or HIV-positive adults, U.S. researchers said. CD4+ T lymphocytes, or CD4 T cells, are the brains of the immune system, coordinating its activity when the body comes under attack. They are also the cells that are attacked by HIV -- the virus slowly eats away at CD4 T cells, weakening the immune system. But the immune systems of HIV/AIDS patients face another enemy as well -- stress, which can accelerate CD4 T...

2008-06-30 09:03:37

RICHMOND, Calif., June 30 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. announced today the publication of data demonstrating that human immune system cells (CD4 T-cells) can be made resistant to HIV infection by treatment with zinc finger DNA-binding protein nucleases (ZFN(TM)). The data suggest that the ZFN approach, which results in the permanent modification of the CCR5 gene encoding an important receptor for HIV infection, is a promising strategy for the treatment of HIV/AIDS....

2008-06-26 09:03:12

Cytheris SA, a clinical stage biopharmaceutical company focused on research and development of new therapies for immune modulation, today announced the publication of data from a phase 1 dose escalation study evaluating the effects of IL-7 therapy on human lymphocytes in subjects with non-hematologic, non-lymphoid cancer refractory to standard therapy. The results of this study, performed in collaboration with U.S. National Cancer Institute (NCI) investigators lead by Claude Sportes, Crystal...

2008-06-18 18:00:00

SEATTLE, June 18 /PRNewswire/ -- Researchers describe the first successful use of a human patient's cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission. A team led by Cassian Yee, M.D., an associate member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, reports these findings in the June 19 issue of the New England Journal of Medicine. Yee and colleagues removed CD4+ T cells, a type of white...

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2008-02-11 14:17:09

Scientists at the National Institute of Allergy and Infectious Diseases (NIAID) reported Sunday they have discovered another mechanism used by the AIDS virus to attack cells. More than 33 million people are infected with HIV globally and 25 million have died of AIDS.  Currently, there is no cure or vaccine.  The NIAID team said their findings could open the door to new ways of fighting HIV. The human immunodeficiency virus, or HIV, attacks immune system cells, or lymphocytes, known...

2007-01-12 12:00:20

Pipex Pharmaceuticals, Inc. (OTCBB: PPXP), a specialty pharmaceutical company developing innovative late-stage drug candidates for the treatment of neurologic and fibrotic diseases, announced today that it has completed the previously disclosed planned acquisition of its majority-owned subsidiary, Effective Pharmaceuticals, Inc. (EPI). As a result of this acquisition, Pipex has gained broader control of Effective Pharmaceuticals, Inc.'s (EPI) lead products, Anti-CD4 802-2 and CORRECTA(TM),...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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