Latest CD4 Stories
In a first-of-its-kind health campaign in Uganda, researchers from the University of North Carolina at Chapel Hill show that adults with HIV who had less severe infections could work more hours per week, and their children were more likely to be enrolled in school.
In wealthy countries, antiretroviral therapy (ART) has transformed AIDS into an often-manageable chronic condition, as patients can receive both the therapeutics and the constant monitoring that ensures the therapies remain effective.
The hallmark loss of helper CD4+ T cells during human immunodeficiency virus (HIV) infection may be a red herring for therapeutics.
Using data from the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE), Jim Young and colleagues from The Opportunistic Infections Project Team of COHERE show in this week's PLoS Medicine that in successfully treated patients, the risk of a new AIDS event or death follows a CD4 cell count gradient in patients with viral suppression.
In a study investigating immune response in cancer, researchers from Moffitt Cancer Center in Tampa, Fla., and the University of South Florida have found that interaction between the immune system's antigen-specific CD4 T cells and myeloid-derived suppressor cells (MDSC) - cells that play a major role in cancer-related immune suppression - dramatically change the nature of MDSC-mediated suppression.
- The act of sweetening by admixture of some saccharine substance.