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Latest CD4 Stories

2011-03-14 16:18:19

Elevated p21 expression blocks key steps in viral life cycle Elevated levels of p21, a protein best known as a cancer fighter, may be involved in the ability of a few individuals to control HIV infection with their immune system alone. In a paper in the April edition of the Journal of Clinical Investigation, researchers from the Massachusetts General Hospital (MGH) Infectious Disease Division and the Ragon Institute of MGH, MIT and Harvard report that CD4 T cells from HIV controllers, while...

2011-03-03 06:00:00

RICHMOND, Calif., March 3, 2011 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced that data from its programs to develop ZFN-based therapeutic approaches for the treatment of HIV/AIDS were discussed in four oral presentations at the 18th Conference on Retroviruses and Opportunistic Infections (CROI), held in Boston from February 27 to March 2, 2011. "SB-728-T is a key addition to the toolbox of technologies required to move from the bone marrow transplant setting...

2011-02-28 07:30:00

RICHMOND, Calif., Feb. 28, 2011 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today the presentation of positive preliminary clinical data from its Phase 1 trial (SB-728-902). The trial is being conducted in immunologic non-responders, HIV-infected subjects who are currently on highly active antiretroviral therapy (HAART) and have undetectable levels of virus but suboptimal CD4+ T-cell counts. The study is designed to evaluate safety and clinical outcomes of...

2011-02-25 13:03:10

A new finding from scientists at the National Institutes of Health could help efforts to design vaccines and other prevention tools to block HIV in the early stages of sexual transmission, before infection takes hold. Researchers at the NIH National Institute of Allergy and Infectious Diseases have helped explain genetic differences that can distinguish some early-transmitting HIVs"”viruses found in an infected individual within the first month after infection"”from forms of HIV...

2011-01-24 15:11:20

HIV's Trickery within the Macrophage Revealed HIV adapts in a surprising way to survive and thrive in its hiding spot within the human immune system, scientists have learned. While the finding helps explain why HIV remains such a formidable foe after three decades of research "“ more than 30 million people worldwide are infected with HIV "“ it also offers scientists a new, unexpected way to try to stop the virus. The work by researchers at the University of Rochester Medical...

2010-12-09 07:00:00

DURHAM, N.C., Dec. 9, 2010 /PRNewswire/ -- Argos Therapeutics announced today that its Arcelis HIV immunotherapy, AGS-004, showed feasibility in in vitro models to generate fully functional dendritic cells (DC) from viremic patients. Argos plans to start a Phase 1 trial of AGS-004 to test the prevention or delay in the initiation of antiretroviral therapy (ART) in ART-naive patients. Data were presented orally and in a poster at the HIV DART(TM) 2010 Conference in Los Cabos, Mexico....

2010-11-24 11:45:44

Gladstone investigators solve long-standing HIV mystery Scientists at Gladstone Institute of Virology and Immunology have solved a long-standing mystery about HIV infection"“namely how HIV promotes the death of CD4 T cells. It is the loss of this critical subset of immune cells that leads to the development of AIDS. Most immune cells that die during HIV infection are seemingly not infected, a phenomenon formerly described as "bystander cell killing." Now the Gladstone scientists report...

2010-11-24 11:40:55

Researchers appear to have an explanation for a longstanding question in HIV biology: how it is that the virus kills so many CD4 T cells, despite the fact that most of them appear to be "bystander" cells that are themselves not productively infected. That loss of CD4 T cells marks the progression from HIV infection to full-blown AIDS, explain the researchers who report their findings in studies of human tonsils and spleens in the November 24th issue of Cell, a Cell Press publication. "In...

2010-11-22 18:59:58

Johns Hopkins study finds later treatment adds tens of thousands of dollars in care HIV infected patients whose treatment is delayed not only become sicker than those treated earlier, but also require tens of thousands of dollars more in care over the first several years of their treatment. "We know that it's important clinically to get people into care early because they will stay healthier and do better over the long run," says Kelly Gebo, M.D., M.P.H., an associate professor of medicine in...

2010-10-31 00:13:18

The CD4 Initiative at Imperial College, London, funded by Bill and Melinda Gates Foundation grants, is nearing a major breakthrough in HIV/AIDS care by developing a simple, inexpensive CD4 point-of-care test specifically designed for resource-poor settings. ImmunoSite Technologies has been developing QA materials for the innovative, disposable test kit. Fort Lauderdale, FL (PRWEB) October 30, 2010 Since early 2007, researchers from ImmunoSite Technologies (IST) have been working with a...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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