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Latest CD4 Stories

2010-11-24 11:40:55

Researchers appear to have an explanation for a longstanding question in HIV biology: how it is that the virus kills so many CD4 T cells, despite the fact that most of them appear to be "bystander" cells that are themselves not productively infected. That loss of CD4 T cells marks the progression from HIV infection to full-blown AIDS, explain the researchers who report their findings in studies of human tonsils and spleens in the November 24th issue of Cell, a Cell Press publication. "In...

2010-11-22 18:59:58

Johns Hopkins study finds later treatment adds tens of thousands of dollars in care HIV infected patients whose treatment is delayed not only become sicker than those treated earlier, but also require tens of thousands of dollars more in care over the first several years of their treatment. "We know that it's important clinically to get people into care early because they will stay healthier and do better over the long run," says Kelly Gebo, M.D., M.P.H., an associate professor of medicine in...

2010-10-31 00:13:18

The CD4 Initiative at Imperial College, London, funded by Bill and Melinda Gates Foundation grants, is nearing a major breakthrough in HIV/AIDS care by developing a simple, inexpensive CD4 point-of-care test specifically designed for resource-poor settings. ImmunoSite Technologies has been developing QA materials for the innovative, disposable test kit. Fort Lauderdale, FL (PRWEB) October 30, 2010 Since early 2007, researchers from ImmunoSite Technologies (IST) have been working with a...

2010-10-08 02:22:15

In a technical tour de force, structural biologists funded by the National Institutes of Health have determined the three-dimensional structure of a molecule involved in HIV infection and in many forms of cancer. The high-resolution structure sheds light on how the molecule functions and could point to ways to control its activity, potentially locking out HIV and stalling cancer's spread. The molecule, CXCR4, is part of a large family of proteins called G-protein coupled receptors (GPCRs)....

2010-07-20 08:30:00

VIENNA and NEW YORK, July 20 /PRNewswire/ -- The Abzyme Research Foundation announces today that Dr. Sudhir Paul, a scientist at University of Texas Houston Medical School, has identified an important immunological deficiency in HIV-infected patients and has created a promising HIV vaccine candidate that rectifies the deficiency. The discoveries were presented on July 19th and 20th, 2010 at the XVII International AIDS Society Conference in Vienna, Austria. The HIV vaccine candidate has...

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2010-07-18 09:41:53

Microfluidic device uses antibodies to 'capture' white blood cells called T cells affected by HIV UC Davis biomedical engineer Prof. Alexander Revzin has developed a "lab on a chip" device for HIV testing. Revzin's microfluidic device uses antibodies to "capture" white blood cells called T cells that are affected by HIV. In addition to physically binding these cells the test detects the types and levels of inflammatory proteins (cytokines) released by the cells. Revzin's team collaborated...

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2010-07-09 10:53:44

Discovery to advance HIV vaccine design, antibody therapy for other diseases Scientists have discovered two potent human antibodies that can stop more than 90 percent of known global HIV strains from infecting human cells in the laboratory, and have demonstrated how one of these disease-fighting proteins accomplishes this feat. According to the scientists, these antibodies could be used to design improved HIV vaccines, or could be further developed to prevent or treat HIV infection. Moreover,...

2010-07-06 06:00:00

RICHMOND, Calif., July 6 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced the publication of data demonstrating the preclinical efficacy of a human stem cell therapy for human immunodeficiency virus (HIV) based on its proprietary zinc finger DNA-binding protein nuclease (ZFN) technology. The ZFN approach enables the permanent disruption of the CCR5 gene, which encodes an important receptor for HIV infection, in all the cell types comprising the immune system...

2010-05-14 12:52:12

HIV disease tends to progress at a faster rate in infected individuals who consume two or more alcoholic drinks a day, according to an important new paper in AIDS Research and Human Retroviruses, a peer-reviewed journal published by Mary Ann Liebert, Inc. The article is available free online. The article, entitled "Alcohol Use Accelerates HIV Disease Progression," clearly demonstrates that frequent alcohol use, defined as two or more drinks daily, is associated with declining CD4+ cell counts...

2010-05-06 10:00:00

MELBOURNE, Australia, May 6 /PRNewswire/ -- The use of rapid point-of-care diagnostic tests for the measurement of CD4 T-cells, a marker of the immune system will be an important factor in improving the lives of people living with HIV and AIDS especially in developing and resource-poor countries. Speaking on global diagnostics at the Bio2010 International Convention in Chicago, Burnet Institute's Associate Professor David Anderson said point-of-care tests that are cheap, easy to use and...


Word of the Day
bellycheer
  • Good cheer; viands.
  • To revel; to feast.
The word 'bellycheer' may come from 'belle cheer', "good cheer".
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