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Latest CD4 Stories

2010-10-08 02:22:15

In a technical tour de force, structural biologists funded by the National Institutes of Health have determined the three-dimensional structure of a molecule involved in HIV infection and in many forms of cancer. The high-resolution structure sheds light on how the molecule functions and could point to ways to control its activity, potentially locking out HIV and stalling cancer's spread. The molecule, CXCR4, is part of a large family of proteins called G-protein coupled receptors (GPCRs)....

2010-07-20 08:30:00

VIENNA and NEW YORK, July 20 /PRNewswire/ -- The Abzyme Research Foundation announces today that Dr. Sudhir Paul, a scientist at University of Texas Houston Medical School, has identified an important immunological deficiency in HIV-infected patients and has created a promising HIV vaccine candidate that rectifies the deficiency. The discoveries were presented on July 19th and 20th, 2010 at the XVII International AIDS Society Conference in Vienna, Austria. The HIV vaccine candidate has...

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2010-07-18 09:41:53

Microfluidic device uses antibodies to 'capture' white blood cells called T cells affected by HIV UC Davis biomedical engineer Prof. Alexander Revzin has developed a "lab on a chip" device for HIV testing. Revzin's microfluidic device uses antibodies to "capture" white blood cells called T cells that are affected by HIV. In addition to physically binding these cells the test detects the types and levels of inflammatory proteins (cytokines) released by the cells. Revzin's team collaborated...

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2010-07-09 10:53:44

Discovery to advance HIV vaccine design, antibody therapy for other diseases Scientists have discovered two potent human antibodies that can stop more than 90 percent of known global HIV strains from infecting human cells in the laboratory, and have demonstrated how one of these disease-fighting proteins accomplishes this feat. According to the scientists, these antibodies could be used to design improved HIV vaccines, or could be further developed to prevent or treat HIV infection. Moreover,...

2010-07-06 06:00:00

RICHMOND, Calif., July 6 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced the publication of data demonstrating the preclinical efficacy of a human stem cell therapy for human immunodeficiency virus (HIV) based on its proprietary zinc finger DNA-binding protein nuclease (ZFN) technology. The ZFN approach enables the permanent disruption of the CCR5 gene, which encodes an important receptor for HIV infection, in all the cell types comprising the immune system...

2010-05-14 12:52:12

HIV disease tends to progress at a faster rate in infected individuals who consume two or more alcoholic drinks a day, according to an important new paper in AIDS Research and Human Retroviruses, a peer-reviewed journal published by Mary Ann Liebert, Inc. The article is available free online. The article, entitled "Alcohol Use Accelerates HIV Disease Progression," clearly demonstrates that frequent alcohol use, defined as two or more drinks daily, is associated with declining CD4+ cell counts...

2010-05-06 10:00:00

MELBOURNE, Australia, May 6 /PRNewswire/ -- The use of rapid point-of-care diagnostic tests for the measurement of CD4 T-cells, a marker of the immune system will be an important factor in improving the lives of people living with HIV and AIDS especially in developing and resource-poor countries. Speaking on global diagnostics at the Bio2010 International Convention in Chicago, Burnet Institute's Associate Professor David Anderson said point-of-care tests that are cheap, easy to use and...

2010-04-29 13:21:45

Limited success in modeling the behavior of the complex, unusual and unpredictable HIV virus has slowed efforts to develop an effective vaccine to prevent AIDS. A new improved modeling system, developed by Chinese researchers, which attempts to incorporate more of the virus' random behavioral dynamics, suggests that a particular type of T cell could be useful in the development of an AIDS vaccine. New research published today, Thursday 29 April, in New Journal of Physics (co-owned by the...

2010-04-27 02:01:00

MELBOURNE, Australia, April 27 /PRNewswire/ -- Scientists at Australia's Burnet Institute have developed a rapid point-of-care diagnostic test for the measurement of CD4 T-cells, a marker of the immune system for people living with HIV and AIDS. Based on the measurement of cell-associated CD4 protein in whole blood samples such as a finger prick, the kit will enable patients to receive appropriate treatment earlier without having to wait for reference laboratory test results which...

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2010-04-03 09:29:51

Finding looks at clade C gp120; also reveals unusual autoreactivity between 21c antibody and CD4 receptor Scientists from the California Institute of Technology (Caltech) have provided the first-ever glimpse of the structure of a key protein"”gp120"”found on the surface of a specific subgroup of the human immunodeficiency virus, HIV-1. In addition, they demonstrated that a particular antibody to gp120 makes contact not only with the protein, but with the CD4 receptor that gp120...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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