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Latest CD4 Stories

2009-05-08 08:30:55

Finding may explain how immune system restricts spread of HIV, hepatitis Why is the immune system able to fight off some viruses but not others, leading to chronic, life-threatening infections like HIV and hepatitis C? A new UCLA AIDS Institute study suggests the answer lies in a protein called interleukin-21 (IL-21), a powerful molecule released by immune cells during chronic infection. Published May 7 in the online edition of Science, the finding could explain how the immune system limits...

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2009-04-16 06:05:00

A new report from the Naval Medical Center in San Diego said that CD4+ cell counts among newly-diagnosed HIV patients in the U.S. fell from 1985 to 2007, suggesting the virus may be growing more virulent. CD4+ cells are immune-system cells that are indicate the severity of HIV infection.  As the infection advances, CD4+ cell counts decline. The findings support previous research indicating that patients beginning HIV treatment in recent years may have lower CD4+ cell counts at diagnosis,...

2009-04-15 07:41:59

Montreal, April 14 2009 "“ Begin treatment as early as possible: this general common sense rule seems to apply to most diseases except HIV-AIDS, which is only treated once a certain number of immune cells called "CD4+" cells have disappeared. The results of a North American study, which involved the team of Dr. Marina Klein of the Research Institute of the MUHC, run contrary to this consensus. The findings show that the risk of death in seropositive patients decreases by 69% to 94% if...

2009-04-10 08:32:49

The first antiretroviral treatments appeared in 1996. Since then, new and better drugs have been discovered that have almost turned AIDS into a chronic disease. Nevertheless, there is still room to improve the performance of the the therapeutic strategies used in clinical practice. This is shown by a study published in the online edition of The Lancet, suggesting that early administration of antiretroviral treatment reduces the rate of AIDS development and death in HIV-positive patients by...

2009-02-11 09:06:12

Providing a synthetic form of the immune system protein interleukin-2 (IL-2) to HIV-infected individuals already taking combination antiretroviral therapy boosts their numbers of CD4+ T cells, the key white blood cells destroyed by HIV, but fails to reduce their risk of HIV-associated opportunistic diseases or death compared with combination antiretroviral therapy alone.These are the findings of two large international clinical trials presented today at the Conference on Retroviruses and...

2009-02-03 06:00:00

Therapeutic Approach Provides HIV-Resistant Immune Cells RICHMOND, Calif., Feb. 3 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that its collaborators at the University of Pennsylvania have opened a Phase 1 clinical trial to evaluate SB-728-T for the treatment of HIV/AIDS. Based on Sangamo's zinc finger DNA-binding protein nuclease (ZFN) technology, SB-728-T has been shown in an animal model of HIV infection to lead to an increase in CD4+ T-cell...

2009-01-07 07:15:00

WALTHAM, Mass., Jan. 7 /PRNewswire-FirstCall/ -- Inverness Medical Innovations, Inc. (NYSE: IMA), a leading provider of near-patient diagnostics, monitoring and health management solutions, has introduced the pima(TM) analyzer, a unique test platform which allows immunological testing at Point-of-Care. The initial application of the instrument will be a first of its kind CD4 cell enumeration test. The instrument is one of several novel technologies under development at an Inverness...

2008-10-28 18:00:28

WASHINGTON and RICHMOND, Calif., Oct. 28 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. announced today the presentation of data demonstrating that human CD4 T-cells can be made permanently resistant to HIV infection by treatment with zinc finger DNA-binding protein nucleases (ZFN(TM)) resulting in an increase in CD4 T-cell counts and a reduction in viral load in an animal model of HIV infection. The presentation, entitled, "Establishment of HIV Resistant CD4 T-cells Using Engineered...

2008-10-27 06:00:07

By Steve Sternberg WASHINGTON -- A new analysis of the best time to begin HIV treatment found that starting early sharply improves survival, doctors said Sunday. Doctors say the new evidence is certain to prompt many doctors to change the way they treat patients, and to prompt health officials to begin examining the evidence underlying guidelines for treating the AIDS virus. The study of 8,374 patients in the USA and Canada showed that those treated later in the course of HIV infection...

2008-09-22 18:00:34

A simple test given to HIV/AIDS patients in southern Africa could extend their lives by nearly a year and save health-care costs at the same time, according to a new study by researchers at the Stanford University School of Medicine and the Palo Alto Veterans Affairs Health Care System. The technique, known as the CD4 test, would be particularly valuable if it were given to patients early in their disease, before they became ill with an AIDS-related infection, the researchers found. Use...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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