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Latest CDKN1B Stories

2011-06-09 23:33:23

Blocking cyclin D1 might help sensitize tumors to radiation Scientists at Dana-Farber Cancer Institute have uncovered a new role for a key cancer protein, a finding that could pave the way for more-effective radiation treatment of a variety of tumors. Many cancers are driven in part by elevated levels of cyclin D1, which allow the cells to escape growth controls and proliferate abnormally. In the new research, reported in the June 9 issue of Nature, researchers discovered that cyclin D1 also...

2008-08-27 09:00:31

By Liu, Jingjing Zhang, Yiyue; Qin, Genji; Tsuge, Tomohiko; Sakaguchi, Norihiro; Luo, Guo; Sun, Kangtai; Shi, Dongqiao; Aki, Shiori; Zheng, Nuoyan; Aoyama, Takashi; Oka, Atsuhiro; Yang, Weicai; Umeda, Masaaki; Xie, Qi; Gu, Hongya; Qu, Li-Jia Following meiosis, plant gametophytes develop through two or three rounds of mitosis. Although the ontogeny of gametophyte development has been defined in Arabidopsis thaliana, the molecular mechanisms regulating mitotic cell cycle progression are not...

2008-07-21 12:01:26

Sound Pharmaceuticals has received a R&D contract award from the Office of Naval Research for approximately $1.6 million to optimize its lead drug candidate for hearing regeneration. Sound Pharmaceuticals has developed a proprietary technology for regenerating auditory sensory cells within the inner ear of mammals involving p27Kip1, a cyclin dependent kinase inhibitor or CKI. In 2005, the Office of Naval Research began funding this hearing regeneration project. This new funding brings...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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