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Latest Cell cycle checkpoint Stories

2009-01-06 11:47:52

Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following DNA repair. Since Ddk is often deregulated in human cancers, this new understanding of its role in DNA damage control could help shape new cancer therapies. The research was published in the December 24 issue of Molecular Cell.Accurate DNA...


Word of the Day
upstander
  • A person who stands up for something, as contrasted to a bystander who remains inactive.
  • One of the upright handlebars on a traditional Inuit sled.
The word 'upstander' in the first sense here is a play on the word 'bystander' and the idea of 'standing up' for something.