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Latest Cell signaling Stories

2012-06-22 16:08:18

Protein binds to growth factor receptor, priming it for normal function; Likely tie to 4 cancers Once considered merely a passive link between proteins that matter, Grb2 - pronounced "grab2" - actually lives up to its nickname with its controlling grip on an important cell signaling pathway, scientists at The University of Texas MD Anderson Cancer Center report in the June 22 issue of Cell. "Grb2 is a switch that controls normal signaling through the fibroblast growth factor receptor...

2012-06-21 21:05:39

Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single gene to produce or code multiple types of protein variants. The discovery, published in the June 27, 2012 issue of Molecular Cell, suggests the new pathway might be a fruitful target for new cancer drugs. Signal transduction in the cell involves kinases and phosphatases,...

2012-06-21 21:01:16

Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites. Researchers from Cincinnati Children's Hospital Medical Center report their findings online June 21 in Chemistry & Biology. The scientists named their lead drug candidate "Rhosin" and hope future testing shows it to be promising for the treatment of various cancers or nervous system...

2012-06-19 00:03:38

International collaboration puts molecular face on enzyme family that allows plants to adjust quickly to herbivore attack or changes in growing conditions Science has known about plant hormones since Charles Darwin experimented with plant shoots and showed that the shoots bend toward the light as long as their tips, which are secreting a growth hormone, aren´t cut off. But it is only recently that scientists have begun to put a molecular face on the biochemical systems that...

2012-06-12 06:23:43

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have identified several proteins that help regulate cells´ response to light–and the development of night blindness, a rare disease that abolishes the ability to see in dim light. In the new studies, published recently in the journals Proceedings of the National Academy of Sciences (PNAS) and The Journal of Cell Biology, Scripps Florida scientists were able to show that a family of...

2012-05-16 22:24:14

Scientists optimistic that targeting pathway's cellular transcription process will lead to death of multiple myeloma cells Researchers at NYU School of Medicine have identified a target for slowing the progression of multiple myeloma by using currently available drugs. Published recently in Nature Cell Biology, the study reveals a pathway that, if deactivated, may help slow the development of the disease. "We have the ability to target this pathway with drugs that already exist,"...

2012-05-10 23:00:47

The human body does a great job of generating new cells to replace dead ones but it is not perfect. Cells need to communicate with or signal to each other to decide when to generate new cells. Communication or signaling errors in cells lead to uncontrolled cell growth and are the basis of many cancers. At The University of Texas Health Science Center at Houston (UTHealth) Medical School, scientists have made a key discovery in cell signaling that is relevant to the fight against melanoma...

2012-04-30 14:51:23

Berkeley Lab scientists demonstrate the promise of synchrotron infrared spectroscopy of living cells for medical applications Knowing how a living cell works means knowing how the chemistry inside the cell changes as the functions of the cell change. Protein phosphorylation, for example, controls everything from cell proliferation to differentiation to metabolism to signaling, and even programmed cell death (apoptosis), in cells from bacteria to humans. It´s a chemical process that...

2012-04-27 11:20:11

Bacteria provide a well-known playground for scientists and the evolution of these earliest life forms has shed important perspective on potential therapies for some of the most common, deadly diseases. Researchers at Case Western Reserve University School of Medicine have now discovered that, the gas nitric oxide (NO), produced in all cells of the human body for natural purposes, plays a fundamental regulatory role in controlling bacterial function, via a signaling mechanism called...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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