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Last updated on April 21, 2014 at 1:20 EDT

Latest Cell signaling Stories

2013-11-19 12:37:11

Adelaide researchers have found that a specific gene plays an important role in suppressing lymphoma, a type of blood cell cancer. The caspase-2 gene is related to a family of proteins that are essential for the self-destruction of cells in the body, a process known as apoptosis. Caspase-2 was first discovered almost 20 years ago by Professor Sharad Kumar, Co-Director of the Centre for Cancer Biology within SA Pathology, Affiliate Professor in the University of Adelaide's schools of...

2013-10-21 10:08:34

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23. Mutant forms of the protein KRAS are found in approximately 30 percent of all cancers. They are responsible for many of the hallmarks of these...

2013-10-20 23:00:41

Transparency Market Research Published New Market Research Report "Global Apoptosis Market - Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019. Browse the full report at http://www.transparencymarketresearch.com/apoptosis-market.html Albany, New York, USA (PRWEB) October 21, 2013 Apoptosis is the process of programmed cell death that occurs due to biochemical events. There are a variety of changes, also referred to as morphology, that occur in a cell leading...

2013-10-08 13:25:02

Mechanism meant to maintain efficiency of brain network involved in neurodegenerative disease Scientists at the Montreal Neurological Institute and Hospital-The Neuro, McGill University, have made important discoveries about a cellular process that occurs during normal brain development and may play an important role in neurodegenerative diseases. The study’s findings, published in Cell Reports, a leading scientific journal, point to new pathways and targets for novel therapies for...

2013-10-08 10:09:58

For more than a decade the research group of Brown University Professor Walter Atwood has doggedly pursued the workings of the JC polyomavirus, which causes a disease called PML that fatally degrades the central nervous system of patients with weakened immune systems. In a study published online Oct. 2 in the Journal of Virology, his team describes how it gains entry into cells: It breaks in via certain receptors of the neurotransmitter serotonin called 5-HT2 receptors. Atwood, lead author...

Three American Scientists Win 2013 Nobel Prize In Physiology Or Medicine
2013-10-07 11:11:24

Brett Smith for redOrbit.com - Your Universe Online Three scientists at American universities were awarded the 2013 Nobel Prize in Physiology or Medicine for their work describing the cellular machinery behind the transport and secretion of proteins in the body’s cells. Based on their experiments with yeast, the scientists – Randy W. Schekman from the University of California at Berkeley, Thomas C. Südhof from Stanford University and James E. Rothman from Yale University -- were...

2013-10-03 08:29:30

-- Brings Omeros' Total to 52 Class A Orphans and Opens Way to New Oral Drugs to Treat Diabetes and Osteoporosis -- SEATTLE, Oct. 3, 2013 /PRNewswire/ -- Omeros Corporation (NASDAQ: OMER) today announced that it has identified compounds that functionally interact with each of six additional orphan G protein-coupled receptors (GPCRs) that have been linked to a wide range of diseases in the areas of neurologic disorders, cardiovascular disease and oncology. Identification of...

2013-09-09 20:30:18

While great strides have been achieved in cancer treatment, scientists are looking for the new targets and next generation of therapeutics to stop this second leading cause of death nationwide. A new platform for drug discovery has been developed through a collaborative effort linking chemists at NYU and pharmacologists at USC. In a study appearing in Proceedings of the National Academy of Sciences, the research groups of Paramjit Arora, a professor in NYU's Department of Chemistry, and...

2013-08-20 23:21:18

ChanTest, a Contract Research Organization and world leader in ion channel drug safety and discovery, announces initiation of a project funded by the US Food and Drug Administration’s (FDA) Center for Tobacco Products (CTP). Cleveland (PRWEB) August 20, 2013 ChanTest, a Contract Research Organization and world leader in ion channel drug safety and discovery, announces initiation of a project funded by the US Food and Drug Administration’s (FDA) Center for Tobacco Products (CTP)....

2013-08-13 11:35:26

Neural stem cells transplanted into tumor-bearing rats can hinder tumor cell growth and prolife-ration; however, the mechanism remains unclear. Abnormal activation of the Ras/Raf/Mek/Erk signaling cascade plays an important role in glioma. Inhibition of this aberrant activity could effectively hinder glioma cell proliferation and promote cell apoptosis. To investigate the mechanism of glioblastoma treatment by neural stem cell trans-plantation with respect to the Ras/Raf/Mek/Erk pathway, Hua...