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Latest Cell signaling Stories

Xray Maps GPCR
2013-12-20 12:57:28

redOrbit Staff & Wire Reports - Your Universe Online Researchers have used one of the brightest X-ray sources in the world to map the three-dimensional structure of an important cellular gatekeeper known as a G protein-coupled receptor, or GPCR, in a more natural state than has been previously possible. The new technique, described Friday in the journal Science, is a major leap forward in exploring GPCRs, a vast, hard-to-study family of proteins that plays a key role in human health...

2013-12-18 11:38:03

If scientists can control cellular functions such as movement and development, they can cripple cells and pathogens that are causing disease in the body. Supported by National Institutes of Health grants, researchers at Oak Ridge National Laboratory (ORNL), the University of Tennessee (UT), and the UT–ORNL Joint Institute for Computational Sciences (JICS) discovered a molecular “switch” in a receptor that controls cell behavior using detailed molecular dynamics simulations on a...

2013-12-18 11:36:08

Imagine kicking a cocaine addiction by simply popping a pill that alters the way your brain processes chemical addiction. New research from the University of Pittsburgh suggests that a method of biologically manipulating certain neurocircuits could lead to a pharmacological approach that would weaken post-withdrawal cocaine cravings. The findings have been published in Nature Neuroscience. Researchers led by Pitt neuroscience professor Yan Dong used rat models to examine the effects of...

2013-12-16 12:10:42

Research indicates e-cigarettes may not significantly reduce risk for heart disease Nicotine, the major addictive substance in cigarette smoke, contributes to smokers' higher risk of developing atherosclerosis, the primary cause of heart attacks, according to research to be presented Sunday, Dec. 15, at the American Society for Cell Biology Annual Meeting in New Orleans. These findings suggest that e-cigarettes, the battery-powered devices that deliver nicotine in steam without the...

2013-12-05 23:40:35

The N-methyl-D-aspartic acid (NMDA) receptor dysfunction in the brain of aged animals has been shown. In older rodents, N-methyl-D-aspartate receptor 2B subunit gene expression declines significantly associated with memory impairment. To further reveal this process, Dr. Chunxia Li and colleagues from East China Normal University, China analyzed gene expression profiles in the neocortex of aged Tg mice. Pathway and signal-net analyses identified multiple pathways altered in the transgenic...

2013-12-04 23:33:18

A University of Colorado Cancer Center study published online ahead of print in the journal Nutrition and Cancer describes the laboratory synthesis of the most active component of grape seed extract, B2G2, and shows this synthesized compound induces the cell death known as apoptosis in prostate cancer cells while leaving healthy cells unharmed. Aurora, Colo. (PRWEB) December 04, 2013 A University of Colorado Cancer Center study published online ahead of print in the journal Nutrition and...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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