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Latest Cell surface receptor Stories

2014-06-23 13:34:53

Duke University Medical Center A team of scientists from Duke Medicine, the University of Michigan and Stanford University has determined the underlying architecture of a cellular signaling complex involved in the body's response to stimuli such as light and pain. This complex, consisting of a human cell surface receptor and its regulatory protein, reveals a two-step mechanism that has been hypothesized previously but not directly documented. The findings, reported on June 22, 2014,...

2014-03-26 11:18:13

The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St. Louis have learned. Scientists were already aware that the type of receptor in question was a potential contributor to these problems – when located on the surfaces of brain cells. Until now, though, the role of the same type of receptor...

2013-11-19 23:03:33

Reportbuyer.com just published a new market research report: Orphan Drugs in Oncology Drug Pipeline Update 2013. London (PRWEB) November 19, 2013 This is a worldwide report on cancer drugs which have now or in the past received orphan drug status. This product will give you unique access not only to those cancer indications in which drugs are being granted orphan drug status, but also detailed insights in to their mechanism of action and developmental strategy. The orphan drug designation...

2013-08-09 09:50:20

Researchers from Tubingen resolve how a plant steroid hormone makes plants grow If one wants to better understand how plants grow, one must analyze the chemistry of life in its molecular detail. Michael Hothorn from the Friedrich-Miescher-Laboratory of the Max Planck Society in Tübingen and his team are doing just that. Their latest work now reveals that a plant membrane receptor requires a helper protein to sense a growth-promoting steroid hormone and to transduce this signal across the...

3D Structure Of Key Drug Target For Diabetes Found
2013-07-18 08:27:10

Scripps Research Institute An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney cells, helps regulate glucose levels in the bloodstream and is the target of potential therapeutic agents for type 2 diabetes. "Our data should change the current view of how drugs are designed with this and related receptors," said TSRI...

BPA Substitute Could Spell Trouble
2013-01-23 10:37:26

Brett Smith for redOrbit.com - Your Universe Online After numerous research studies raised questions over its safety, several states and countries began banning the sale of products containing bisphenol A (BPA), prompting companies in the plastics industry to begin producing products that were “BPA free.” However, a new study from the University of Texas Medical Branch at Galveston (UTMB) shows that a widely used BPA substitute, bisphenol S (BPS), has the same negative...

2012-10-10 22:00:18

Results may help improve drugs for neurological disorders Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide hormones use a novel binding mechanism to activate a class of receptors called G-protein coupled receptors (GPCRs). "The knowledge of how the peptide binds to its receptor should help scientists design...

2012-08-29 07:01:39

Proteins adorning the surfaces of human cells perform an array of essential functions, including cell signaling, communication and the transport of vital substances into and out of cells. They are critical targets for drug delivery and many proteins are now being identified as disease biomarkers–early warning beacons announcing the pre-symptomatic presence of cancers and other diseases. While study of the binding properties of membrane proteins is essential, detailed analysis of...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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