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Last updated on April 20, 2014 at 19:30 EDT

Latest Cell Transplantation Stories

2013-11-25 16:49:03

Pancreatic islet transplantation is a promising therapy for treating type 1 diabetes, but the majority of transplanted cells die soon after they are transplanted. Researchers interested in prolonging the life of these cells co-transplanted endothelial progenitor cells (EPCs) along with pancreatic islet cells and found that the EPCs improved the engraftment of pancreatic islet cells in mouse models, thereby favorably impacting on the cure rate and glycemic control of transplanted islets. The...

2013-09-18 13:09:36

Shortage of livers for transplantation demands better liver cell transplantation A research team in Spain has developed high-yield preparations of viable hepatocytes (liver cells) isolated for transplantation from cryopreserved (frozen), banked neonatal livers that ranged in age from one day to 23 days. The researchers also assessed cell quality and function and found that neonatal hepatocytes show better thawing recovery than hepatocytes isolated from adult livers. The study appears as...

2012-04-18 21:17:04

Autologous (self-donated) mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth when transplanted into patients with diabetes who are suffering from critical limb ischemia caused by peripheral artery disease (PAD), a complication of diabetes. The team of researchers in Seville, Spain who carried out the study published their results in a recent issue of Cell Transplantation (20:10), now freely available on-line at...

2011-09-27 10:36:16

Researchers in Japan have completed a study showing that stem cells derived from deciduous canine teeth and dental pulp can be grafted and produce bone regeneration between parents and offspring. Their results are published in the current issue of Cell Transplantation (20:7), now freely available on-line. "Bone defects can occur for a number of reasons, and autogenous bone grafting - using the patient's own bone - has been a standard approach to treatment," said study corresponding author...

2011-02-22 21:25:23

Transplanting human umbilical cord blood-derived endothelial progenitor cells (EPCs) has been found to "significantly accelerate" wound closure in diabetic mouse models, said a team of Korean researchers publishing in the current issue of Cell Transplantation (19:12), now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ . According to the study's corresponding author, Dr. Wonhee Suh of the CHA University Stem Cell Institute, diabetes is often associated with impaired...

2011-02-17 21:23:06

Two studies published in the current issue of Cell Transplantation (19:12) investigate frontiers of islet cell transplantation for treating diabetes. Researchers in Milan, Italy re-examine the role of bone marrow stem cells in diabetic therapy and islet cell regeneration and Canadian researchers offer improved strategies for optimizing pancreatic islet culture in vitro. Both studies are in the current issue of Cell Transplantation, freely available on-line at...

2011-01-11 14:03:43

Transplanting their own (autologous) bone marrow-derived stem cells into 48 patients with end-stage liver disease resulted in therapeutic benefit to a high number of the patients, report researchers publishing in the current issue of Cell Transplantation (19:11). Yet, the mechanism by which the infusion of CD34+ stem cells improves liver function remains elusive, they say. The study, carried out by a team of researchers in California and in Egypt, is now freely available on-line at...

2010-06-04 13:34:43

A team of researchers from several collaborating Baylor University research centers and from Japan's Okayama Graduate School of Medicine have found a way to more consistently isolate pancreatic islet cells from brain dead donors using ductal injection (DI), a process that immediately cools donor islet cells at the injection site. The more successful islet isolation process resulted in the three type 1-diabetes patients, who received islet cell transplants, becoming insulin independent. Their...

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2010-04-05 12:11:47

A study published in the current issue of Cell Transplantation (19:1) has found that using the FDA-approved contrast agent Indocyanine Green (ICG) to label human embryonic stem cell-derived cardiomyocytes (hESC-CMs) substantially improved efforts to optically track stem cells after transplanting them into heart tissues. The study, carried out by the Departments of Radiology at the University of California and the Technical University of Munich, is freely available on-line at...

2010-02-24 10:24:56

Two studies published in the latest issue of Cell Transplantation (18:12) may lead to new treatments for the treatment of heart diseases. The first study, carried out by a team of Brazilian researchers, found that cell transplantation of bone marrow mononuclear cells (BMMCs) directly into the heart benefited patients suffering from refractory angina. A separate study carried out by researchers in the Peoples' Republic of China found that apelin, a newly described inotropic peptide, improves...