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2014-04-22 14:06:57

Scientists of the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna, together with colleagues of the ETH Zurich, have now shown how double stranded RNA, such as viral genetic information, is prevented from entering the nucleus of a cell. During the immune response against viral infection, the protein ADAR1 moves from the cell nucleus into the surrounding cytoplasm. There it modifies viral RNA to inhibit reproduction of the virus. But how is the human...

2014-04-18 15:52:50

Finding could influence cancer care and regenerative medicine An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. This is the first time the complex has been shown to perform both jobs. This newfound ability could make cyclin B1/Cdk1 an excellent target to control cellular energy production, potentially advancing cancer care and...

2014-04-17 14:28:57

From far away, the top of a leaf looks like one seamless surface; however, up close, that smooth exterior is actually made up of a patchwork of cells in a variety of shapes and sizes. Interested in how these cells individually take on their own unique forms, Caltech biologist Elliot Meyerowitz, postdoctoral scholar Arun Sampathkumar, and colleagues sought to pinpoint the shape-controlling factors in pavement cells, which are puzzle-piece-shaped epithelial cells found on the leaves of...

2014-04-14 10:56:31

Manipulating the metabolic process in cells may compensate for defects that can shorten cell life UAlberta researchers are taking a closer look at how two metabolic pathways interact to increase the lifespan of cells with mitochondrial defects. Magnus Friis (PhD ’10) is the lead author of the study, which was published online on April 10 and will be published in the April 24 issue of Cell Reports. Mitochondria produce energy for cells through oxidative metabolism, but the process...

2014-04-10 23:03:15

The findings from The Scripps Research Institute may lead to new insights into immune deficiency, stroke and diabetes. La Jolla, California (PRWEB) April 10, 2014 A team led by scientists at The Scripps Research Institute (TSRI) has identified a long-sought protein that facilitates one of the most basic functions of cells: regulating their volume to keep from swelling excessively. The identification of the protein, dubbed SWELL1, solves a decades-long mystery of cell biology and points to...

2014-04-09 16:37:59

The findings shed more light on cancer development and metastasis. The push and pull of physical force can cause profound changes in the behavior of a cell. Two studies from researchers working at the UNC Lineberger Comprehensive Cancer Center reveal how cells respond to mechanical manipulation, a key factor in addressing the underlying causes of cancer and other diseases. The studies, published in Nature Cell Biology and the Journal of Immunology, have their roots in a longtime...

2014-04-07 13:34:30

UC Riverside-led research could help identify new anti-malaria strategies A research team led by a cell biologist at the University of California, Riverside has generated a 3D model of the human malaria parasite genome at three different stages in the parasite's life cycle — the first time such 3D architecture has been generated during the progression of the life cycle of a parasite. The parasite that causes malaria in humans is Plasmodium falciparum. The female Anopheles mosquito...

2014-04-04 23:33:51

By illuminating mitochondria, UVA researchers shed light on disease and human health. Charlottesville, VA (PRWEB) April 03, 2014 Under the microscope, they glow like streetlights, forming tidy rows that follow the striations of muscle tissue. They are mitochondria, the powerhouses of cells, and researchers at the University of Virginia School of Medicine have created a method to illuminate and understand them in living creatures like never before. Not only can the researchers make the...

2014-04-03 11:21:51

Stowers team reports genome-wide analysis of genes that drive cell division in a multicellular organism In textbooks, the grand-finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells. This process, called mitosis, is visually stunning to observe under a microscope. Equally stunning to cell biologists are the preparatory steps cells take to ensure that the process occurs safely....

2014-03-28 09:10:41

Mitochondria, long known as "cellular power plants" for their generation of the key energy source adenosine triphosphate (ATP), are essential for proper cellular functions. Mitochondrial defects are often observed in a variety of diseases, including cancer, Alzheimer's disease, and Parkinson's disease, and are the hallmarks of a number of genetic mitochondrial disorders whose manifestations range from muscle weakness to organ failure. Despite a fairly strong understanding of the pathology of...


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Cell (journal)
2012-06-04 14:15:36

Cell is a peer-reviewed scientific journal founded by Benjamin Lewin in January 1974 with the sponsorship of MIT Press. Lewin bought the rights to the journal in 1986 and published it under his own publishing arm Cell Press. Cell Press was sold to Elsevier in 1999, which currently publishes Cell twice monthly. Cell Press publishes several biomedical journals, including Cell, Neuron, Immunity, Molecular Cell, Developmental Cell, Cancer Cell, Current Biology, Structure, Chemistry &...

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Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin