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Latest Cellular differentiation Stories

2012-12-03 17:01:12

The surface of your skin, called the epidermis, is a complex mixture of many different cell types – each with a very specific job. The production, or differentiation, of such a sophisticated tissue requires an immense amount of coordination at the cellular level, and glitches in the process can have disastrous consequences. Now, researchers at the Stanford University School of Medicine have identified a master regulator of this differentiation process. "Disorders of epidermal...

2012-11-30 11:55:59

The study, published in PNAS, opens the way for large-scale screenings to identify targets for cancer therapy. The wing of a fruit fly may hold the key to unraveling the genetic and molecular events that transform a normal cell into a cancerous one. The study, conducted on Drosophila melanogaster by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and led by ICREA researcher Marco Milán, has reproduced each of the steps known to take place when a...

Therapeutic Advancement In The Search For Heart Muscle Progenitor Cells
2012-11-26 11:35:29

Fraunhofer-Gesellschaft Breakthrough in heart research: The research team from Professor Katja Schenke-Layland of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB in Stuttgart has discovered cell surface markers that enable the identification and isolation of living functional cardiovascular progenitor cells (CPCs). For the first time, therapeutically relevant CPCs can be derived from induced-pluripotent stem cells (iPS) cells. CPCs, which are typically only found...

2012-11-02 14:36:43

Caltech-led team discovers enzyme responsible for neural crest cell development During the early developmental stages of vertebrates–animals that have a backbone and spinal column, including humans–cells undergo extensive rearrangements, and some cells migrate over large distances to populate particular areas and assume novel roles as differentiated cell types. Understanding how and when such cells switch their purpose in an embryo is an important and complex goal for...

Stem Cells Produced From Peripheral Blood Through Novel Technique
2012-11-01 12:56:14

Jove (Journal of Visualized Experiments) Stem cells are a valuable resource for medical and biological research, but are difficult to study due to ethical and societal barriers. However, genetically manipulated cells from adults may provide a path to study stem cells that avoid any ethical concerns. A new video-protocol in JoVE (Journal of Visualized Experiments), details steps to generate human induced pluripotent stem cells (iPSC) from cells in the peripheral blood.  The technique...

2012-10-31 03:38:26

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles. Some of these problems are surprisingly common — about 1 percent of all people have a congenital heart defect. This basic research will provide a road map to ultimately allow scientists to grow the cell...

Stem Cells Used To Engineer Cartilage
2012-10-30 06:29:35

Connie K. Ho for redOrbit.com — Your Universe Online Researchers from Duke University Medical Center recently revealed that they have been able to engineer cartilage from pluripotent stem cells, which will help in studies regarding cartilage injury and osteoarthritis. In particular, the pluripotent stem cells were induced and then successful developed to be used in tissue repair. The scientists believe that the induced pluripotent stem cells (iPSCs) could become a source for...

British and Japanese Researchers Awarded The 2012 Nobel Prize For Stem Cell Research
2012-10-08 11:50:50

Lawrence LeBlond for redOrbit.com - Your Universe Online Stem cell research has been a controversial, yet important advance in science and medicine for decades. Scientific research has been carried out in numerous areas pertaining to stem cells, and the work of two such researchers in the field have caught the eye of the most prestigious awards organization in the world. Britain´s Sir John Gurdon and Japan´s Shinya Yamanaka were both awarded the 2012 Nobel Prize for Medicine...

Epigenetics Of Adult Stem Cells Affect Organ Creation
2012-10-03 08:50:32

Alan McStravick for redOrbit.com - Your Universe Online Ask a handful of people about their thoughts and feelings on the use of stem cells for research and therapeutic means and you will find that they each have strong and varying positions on the topic. Outside the scientific community, however, little is known about this highly complex field of research. The politicization of stem cell research accompanied the 1998 discovery that embryonic stem cells, the building blocks of organ,...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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