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Latest Cellular differentiation Stories

2012-09-17 16:58:52

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab). Knowing the architecture of this protein,  PRC2, for Polycomb Repressive Complex 2, should be a boon to its future use in the development of new and improved...

New Efficiency Brought To Stem Cell Reprogramming
2012-09-13 12:35:17

Biologists reveal genes key to development of pluripotency, in single cells Several years ago, biologists discovered that regular body cells can be reprogrammed into pluripotent stem cells – cells with the ability to become any other type of cell. Such cells hold great promise for treating many human diseases. These induced pluripotent stem cells (iPSCs) are usually created by genetically modifying cells to overexpress four genes that make them revert to an immature, embryonic...

2012-09-12 00:55:33

In a new study, Brown University researchers demonstrate a new tool for visually tracking in real-time the transformation of a living population of stem cells into cells of a specific tissue. The “molecular beacons,” which could advance tissue engineering research, light up when certain genes are expressed and don´t interfere with the development or operation of the stem cells. A novel set of custom-designed “molecular beacons” allows scientists to monitor gene...

2012-08-31 13:41:11

Stowers scientists show how pluripotent stem cells mobilize in wounded planarian worms, to better understand stem cell behavior in regeneration and disease The skin, the blood, and the lining of the gut–adult stem cells replenish them daily. But stem cells really show off their healing powers in planarians, humble flatworms fabled for their ability to rebuild any missing body part. Just how adult stem cells build the right tissues at the right times and places has remained largely...

2012-08-10 23:00:06

IRMO is a leader in traditional orthopedics and cutting-edge innovations in regenerative medicine. The newest breakthrough is performing stem cell harvesting and isolation of adipose mesenchymal stem cells. Boca Raton, FL (PRWEB) August 10, 2012 The Institute of Regenerative and Molecular Orthopedics announced this week that it is one of the few centers performing stem cell harvesting and isolation of adipose mesenchymal stem cells. The procedure could lead to the newest frontier in tissue...

2012-07-09 17:30:09

This approach is described in the work published today in the Journal of Clinical Investigation, which sheds light on the mechanisms that regulate squamous cell carcinoma development Skin squamous cell carcinoma (SCC) is a subtype of very aggressive skin cancers that usually develops in sunexposed body regions, but can also affect a large number of organs such as the bladder, esophagus, lungs etc. However, little is known about the biology of these cells, which consequently makes difficult...

The Key To Self-renewing Skin
2012-07-05 13:45:19

In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life. The findings provide new insights into the role and importance of exosomes and their targeted gene transcripts, and may help point the way to new drugs or therapies for not just skin...


Word of the Day
maffling
  • To stammer.
  • Present participle of maffle, to stammer.
  • A simpleton.
The word 'maffle' may come from a Dutch word meaning 'to move the jaws' or a French word meaning 'having large cheeks'.