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Latest Cellular differentiation Stories

2012-07-09 17:30:09

This approach is described in the work published today in the Journal of Clinical Investigation, which sheds light on the mechanisms that regulate squamous cell carcinoma development Skin squamous cell carcinoma (SCC) is a subtype of very aggressive skin cancers that usually develops in sunexposed body regions, but can also affect a large number of organs such as the bladder, esophagus, lungs etc. However, little is known about the biology of these cells, which consequently makes difficult...

The Key To Self-renewing Skin
2012-07-05 13:45:19

In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life. The findings provide new insights into the role and importance of exosomes and their targeted gene transcripts, and may help point the way to new drugs or therapies for not just skin...

2012-06-06 23:01:00

How a certain type of stem cell mobilizes in the circulation system of older people to repair damage from a heart attack or even to fight the aging process itself could hold the key to treating cardiac and other age-related diseases, according to a new study by researchers at Showa University in Japan. In an article published in the June issue of STEM CELLS Translational Medicine the researchers detail how, for the first time, they were able to home in on a protein called CD271 found on...

2012-06-04 17:49:09

It is well-known that the risks of breast cancer increase dramatically for women over the age of 50, but what takes place at the cellular level to cause this increase has been a mystery. Some answers and the possibility of preventative measures in the future are provided in a new study by researchers at the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab). Mark LaBarge, a cell and molecular biologist in Berkeley Lab´s Life Sciences Division,...

2012-05-22 02:46:55

Brown researchers have discovered mechanical properties of stem cells can foretell what they will become To become better healers, tissue engineering need a timely and reliable way to obtain enough raw materials: cells that either already are or can become the tissue they need to build. In a new study, Brown University biomedical engineers show that the stiffness, viscosity, and other mechanical properties of adult stem cells derived from fat, such as liposuction waste, can predict whether...

2012-05-16 11:20:03

Cell surface protein blows potent cells' cover; targeted drug works in preclinical tests Breast cancer stem cells wear a cell surface protein that is part nametag and part bull's eye, identifying them as potent tumor-generating cells and flagging their vulnerability to a drug, researchers at The University of Texas MD Anderson Cancer Center report online in Journal of Clinical Investigation. "We've discovered a single marker for breast cancer stem cells and also found that it's...

2012-05-15 22:34:01

Some cell types control continued tumor growth, others prepare the way for metastasis A study from Massachusetts General Hospital (MGH) researchers suggests that specific populations of tumor cells have different roles in the process by which tumors make new copies of themselves and grow. In their report in the May 15 issue of Cancer Cell, researchers identify a tumor-propagating cell required for the growth of a pediatric muscle tumor in a zebrafish model and also show that another,...

2012-05-11 15:09:28

New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to the various types of tissues and structures in the body. Researchers from the Georgia Institute of Technology and Emory University found that chromatin compaction is required for proper embryonic stem cell differentiation to occur. Chromatin, which is composed of histone proteins and DNA, packages DNA...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
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