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Latest Cellular differentiation Stories

2012-04-12 11:23:00

In spite of considerable research efforts around the world, we still do not know the determining factors that confer stem cells their main particular features: capacity to self-renew and to divide and proliferate. The scientist Jordi Casanova, head of the “Morphogenesis in Drosophila” lab at IRB Barcelona and CSIC research professor, proposes in an article in the journal Embo Reports that we may be working from an incorrect angle. Casanova´s notion is that stem cells emerge...

2012-04-11 22:16:57

A vast majority of cells in the brain are glial, yet our understanding of how they are generated, a process called gliogenesis, has remained enigmatic. Researchers at Baylor College of Medicine have identified a novel transcripitonal cascade that controls these formative stages of gliogenesis and answered the longstanding question of how glial cells are generated from neural stem cells. "Most people are familiar with neurons, cells that process and transmit information in the brain. Glial...

2012-04-05 21:16:03

Yale researchers show in detail how three genes within human embryonic stem cells regulate development, a finding that increases understanding of how to grow these cells for therapeutic purposes. This process, described in the April 6 issue of the journal Cell Stem Cell, is different in humans than in mice, highlighting the importance of research using human embryonic stem cells. "It is difficult to deduce from the mouse how these cells work in humans," said Natalia Ivanova, assistant...

2012-03-30 07:43:43

4 signaling substances control the transformation of T cells The thymus plays a key role in the body's immune response. It is here where the T lymphocytes or T cells, a major type of immune defense cells, mature. Different types of T cells, designated to perform specific tasks, arise from progenitor cells that migrate to the thymus from the bone marrow. Researchers at the Max Planck Institute of Immunology and Epigenetics in Freiburg have generated artificial thymus tissue in a mouse...

2012-03-14 20:46:55

Researchers at the RIKEN Omics Science Center (OSC) have successfully developed and demonstrated a new experimental technique for producing cells with specific functions through the artificial reconstruction of transcriptional regulatory networks. As an alternative to induced pluripotent stem cells, the technique promises to enable faster and more efficient production of functional cells for use in cancer therapy and a variety of other areas. Starting with the first-ever production of...

2012-03-12 20:17:05

UCLA stem cell researchers have shown that insulin and nutrition keep blood stem cells from differentiating into mature blood cells in Drosophila, the common fruit fly, a finding that has implications for studying inflammatory response and blood development in response to dietary changes in humans. Keeping blood stem cells, or progenitor cells, from differentiating into blood cells is important as they are needed to create the blood supply for the adult fruit fly. The study found that...

2012-03-02 13:06:04

FINDINGS: Devising a novel method to identify potential genetic regulators in planarian stem cells, Whitehead Institute scientists have determined which of those genes affect the two main functions of stem cells. Three of the genes are particularly intriguing because they code for proteins similar to those known to regulate mammalian embryonic stem cells. Such genetic similarity makes planarians an even more attractive model for studying stem cell biology in vivo. RELEVANCE: Stem cells may...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.